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Gene Expression Data
Assay Details
Assay
Reference: J:355262 Kadhim AZ, et al., Transcriptional coactivator MED15 is required for beta cell maturation. Nat Commun. 2024 Oct 8;15(1):8711
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8166937
Gene symbol: Ucn3
Gene name: urocortin 3
Antibody: anti-Ucn3
Results
Specimen 3B CTRL Ucn3: postnatal week 8; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Present 3B CTRL (middle) Expression in beta-cells.
Specimen 3B M15beta Ucn3: postnatal week 8; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: islets of Langerhans Absent 3B M15betaKO (middle) Complete loss of expression.
Specimen S4B P1 CTRL Ucn3: postnatal day 1; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Cell Type Level Pattern Image Note
TS27: islets of Langerhans type B pancreatic cell Present S4B P1 CTRL Expression in beta-cells.
Specimen S4B P1 M15beta Ucn3: postnatal day 1; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS27: islets of Langerhans Absent S4B P1 M15betaKO Complete loss of expression.
Specimen S4B P7 CTRL Ucn3: postnatal day 7; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Present S4B P7 CTRL Expression in beta-cells.
Specimen S4B P7 M15beta Ucn3: postnatal day 7; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: islets of Langerhans Absent S4B P7 M15betaKO Complete loss of expression.
Specimen S4B P14 CTRL Ucn3: postnatal day 14; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Present S4B P14 CTRL Expression in beta-cells.
Specimen S4B P14 M15beta Ucn3: postnatal day 14; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: islets of Langerhans Absent S4B P14 M15betaKO Complete loss of expression.
Specimen S4B 3wk CTRL Ucn3: postnatal week 3; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Present S4B 3wk CTRL Expression in beta-cells.
Specimen S4B 3wk M15beta Ucn3: postnatal week 3; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: islets of Langerhans Absent S4B 3wk M15betaKO Complete loss of expression.
Specimen S4B 4wk CTRL Ucn3: postnatal week 4; Ins1tm1.1(cre)Thor/Ins1+ (more )
Note: Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Present S4B 4wk CTRL
Specimen S4B 4wk M15beta Ucn3: postnatal week 4; Ins1tm1.1(cre)Thor/Ins1+, Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi (more )
Note: Conditional mutant. Double labeled: green - Ucn3; red - Ins1 (assay MGI:8166934) and Ins2 (assay MGI:8166967).
Structure Level Pattern Image Note
TS28: islets of Langerhans Absent S4B 4wk M15betaKO Complete loss of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
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