Clptm1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:357551 Ge Y, et al., Haploinsufficiency of GABA(A) Receptor-Associated Clptm1 Enhances Phasic and Tonic Inhibitory Neurotransmission, Suppresses Excitatory Synaptic Plasticity, and Impairs Memory. J Neurosci. 2024 Aug 7;44(32)
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:7780055
Gene symbol:	Clptm1
Gene name:	cleft lip and palate associated transmembrane protein 1

Results

1F ©

Specimen 1F: postnatal day 22; Clptm1^{tm1a(KOMP)Wtsi}/Clptm1⁺ (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: brain		Present	Ubiquitous	1F	Ubiquitously expressed in brain.
TS28: corpus striatum		Strong		1F	Particularly high expression in olfactory bulb, cortical layers, hippocampus and striatum.
TS28: hippocampus		Strong		1F	Particularly high expression in olfactory bulb, cortical layers, hippocampus and striatum.
TS28: main olfactory bulb		Strong		1F	Particularly high expression in olfactory bulb, cortical layers, hippocampus and striatum.
TS28: neocortex layer		Strong		1F	Particularly high expression in olfactory bulb, cortical layers, hippocampus and striatum.
TS28: cerebellum	Purkinje cell	Strong		1F	High expression in Purkinje cells.

1G beta-gal ©

1G Merge ©

Specimen 1G: postnatal day 22; Clptm1^{tm1a(KOMP)Wtsi}/Clptm1⁺ (more

)
Note: Double labeled: green - Clptm1 reporter; red - Rbfox3 (assay MGI:7780056).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: hippocampus CA1	hippocampal interneuron	Present		1G beta-gal , 1G Merge	Expression in pyramidal cells and interneurons.
TS28: hippocampus CA1	hippocampal pyramidal neuron	Present		1G beta-gal , 1G Merge	Expression in pyramidal cells and interneurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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