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Gene Expression Data
Assay Details
Assay
Reference: J:129202 Dunty WC Jr, et al., Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development. 2008 Jan;135(1):85-94
Assay type: RNA in situ
MGI Accession ID: MGI:7574753
Gene symbol: Ripply2
Gene name: ripply transcriptional repressor 2
Probe: Ripply2 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 4B: embryonic day 9.0 (more )
Note: Double labeled: purple - Ripply2; orange - Dll1 (assay MGI:7574676).
Structure Level Pattern Image Note
TS14: unsegmented mesenchyme Present Regionally restricted 4B Expressed in the anterior border in one or two stripes in prospective somites S0 and S-I, overlapping with Dll1 expression.
Specimen 4C: embryonic day 9.0 (more )
Note: Double labeled: purple - Ripply2; orange - Hes7 (assay MGI:7574755).
Structure Level Pattern Image Note
TS14: unsegmented mesenchyme Present Regionally restricted 4C Expressed in the anterior border, overlapping with Hes7 expression.
Specimen 4D: embryonic day 9.0 (more )
Note: Half of the embryo bisected down the midline. Double labeled: purple - Ripply2; orange - Mesp2 (assay MGI:7574756).
Structure Level Pattern Image Note
TS14: unsegmented mesenchyme Present Regionally restricted 4D Expressed in the anterior border (presumptive somite S-I), mutually exclusive domain from that of Mesp2.
Specimen 4F: embryonic day 8.0 (more )
Note: 0-2 somites.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Present Regionally restricted 4F Expressed in the anterior border (presumptive somite S-I).
Specimen 4G: embryonic day 8.0; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: 0-2 somites.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Present Regionally restricted 4G Expression in S-I was posteriorized relative to the node in Wnt3a-/- mutant.
Specimen 4H: embryonic day 8.2; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 0-2 somites.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Trace Regionally restricted 4H Expression in S-I was nearly absent in LOF mutant (weak to undetectable).
Specimen 4I: embryonic day 8.0; Ctnnb1tm1Mmt/Ctnnb1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 0-2 somites.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Absent 4I Not expressed in GOF mutant.
Specimen not shown: embryonic day 8.2; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 0-2 somites.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Weak Posteriorized expression, compared with the wild-type.
Specimen not shown: embryonic day 8.0; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: 3-6 somites.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Absent Expression was undetectable by 3-6 somites.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory