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Gene Expression Data
Assay Details
Assay
Reference: J:321553 Neupane S, et al., O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biol. 2022 Feb 12;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7567582
Gene symbol: Ccn2
Gene name: cellular communication network factor 2
Antibody: anti-CTGF [E-5] (sc-365970)
Assay notes: Fixation was with 5% acetic acid in ethanol.
Results
Specimen 8A,B,D: embryonic day 14.5; Pofut2tm2.1Bch/Pofut2+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant. Double labeled: red - Ccn2; green - Hspa5 (assay MGI:7567583).
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Strong Regionally restricted 8D , 8B , 8D' , 8A Strong extracellular localization of expresion in proliferative and prehypertrophic zones. Reduced expression in hypertrophic zone. Expression distinct from perinuclear localization of Hspa5.
Specimen 8E,F,H: embryonic day 14.5; Pofut2tm2.1Bch/Pofut2tm2.2Bch, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant. Double labeled: red - Ccn2; green - Hspa5 (assay MGI:7567583).
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 8H , 8F , 8E Extracellular expression with levels slightly reduced in proliferative region but comparable to controls in other regions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/04/2024
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