About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:51656 Marcus RC, et al., Domains of regulatory gene expression and the developing optic chiasm: correspondence with retinal axon paths and candidate signaling cells. J Comp Neurol. 1999 Jan 18;403(3):346-58
Assay type: RNA in situ
MGI Accession ID: MGI:7539088
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Probe: Nkx2-2 probe
Probe preparation: Antisense RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2D: embryonic day 11.0-11.5 (more )
Note: Double labeled: blue - Nkx2-2; brown - Shh (assay MGI:7539094).
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2D Expression is in a telencephalic domain, which includes the septum, the medial ganglionic eminence, and the preoptic area.
TS19: diencephalon Present Regionally restricted 2D Experession is in hypothalamic regions located within the basal plate.
Specimen 2E: embryonic day 11.0-11.5 (more )
Note: Double labeled: blue - Nkx2-2; brown - Shh (assay MGI:7539094).
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2E Expression is in a telencephalic domain, which includes the septum, the medial ganglionic eminence, and the preoptic area.
TS19: diencephalon Present Regionally restricted 2E Experession is in hypothalamic regions located within the basal plate.
Specimen 2F: embryonic day 11.0-11.5 (more )
Note: Double labeled: blue - Nkx2-2; brown - Shh (assay MGI:7539094).
Structure Level Pattern Image Note
TS19: diencephalon ventricular layer Present 2F
TS19: diencephalon Present Regionally restricted 2F Expression is in the subventricular zone and postmitotic layers of the neuroepithelium.
Specimen 2G: embryonic day 11.0-11.5 (more )
Note: Double labeled: blue - Nkx2-2; brown - Nkx2-1 (assay MGI:7539167).
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2G Expression is in a telencephalic domain, which includes the septum, the medial ganglionic eminence, and the preoptic area.
TS19: diencephalon Present Regionally restricted 2G Experession is in hypothalamic regions located within the basal plate.
Specimen 2H: embryonic day 11.0-11.5 (more )
Note: Double labeled: blue - Nkx2-2; brown - Nkx2-1 (assay MGI:7539167).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2H Expression at the front of the brain forms a shallow, inverted "V" shape ventral to the optic stalks.
Specimen 2I: embryonic day 11.0-11.5 (more )
Note: Double labeled: blue - Nkx2-2; brown - Nkx2-1 (assay MGI:7539167).
Structure Level Pattern Image Note
TS19: diencephalon ventricular layer Present Regionally restricted 2I
TS19: diencephalon Present Regionally restricted 2I Expression is in the subventricular zone and postmitotic layers of the neuroepithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory