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Gene Expression Data
Assay Details
Assay
Reference: J:206632 Roberts JM, et al., Splicing factor TRA2B is required for neural progenitor survival. J Comp Neurol. 2014 Feb 1;522(2):372-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531501
Gene symbol: Bhlhe22
Gene name: basic helix-loop-helix family, member e22
Results
Specimen 2P/R: postnatal day 0 (more )
Note: Double labeled: magenta - Bhlhe22; green - Tra2b (assay MGI:7531498).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer II pyramidal neuron Present 2P , 2R Expression in projection neurons in cortical layers 2-5.
TS27: cortical layer III pyramidal neuron Present 2P , 2R Expression in projection neurons in cortical layers 2-5.
TS27: cortical layer IV pyramidal neuron Present 2P , 2R Expression in projection neurons in cortical layers 2-5.
TS27: cortical layer V pyramidal neuron Present 2P , 2R Expression in projection neurons in cortical layers 2-5.
Specimen 3C: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant. Triple labeled: blue - Bhlhe22; red - Bcl11b (assay MGI:7531500); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex pyramidal neuron Present Regionally restricted 3C Expression specific subtypes of projection neurons.
Specimen 3D: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant. Triple labeled: blue - Bhlhe22; red - Bcl11b (assay MGI:7531500); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex pyramidal neuron Weak 3D Numbers of expressing cells reduced compared to control.
Specimen 3E/F/I: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant. Triple labeled: blue - Bhlhe22; red - Bcl11b (assay MGI:7531500); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer II cerebral cortex neuron Present 3I , 3E , 3F
TS27: cortical layer III cerebral cortex neuron Present 3I , 3E , 3F
TS27: cortical layer IV cerebral cortex neuron Present 3I , 3E , 3F
TS27: cortical layer V cerebral cortex neuron Present 3I , 3E , 3F
Specimen 3J/K/N: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant. Triple labeled: blue - Bhlhe22; red - Bcl11b (assay MGI:7531500); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer IV cerebral cortex neuron Weak 3J , 3K , 3N Numbers of expressing cells reduced compared to control.
TS27: cortical layer V cerebral cortex neuron Weak 3J , 3K , 3N Numbers of expressing cells reduced compared to control.
TS27: cortical layer II cerebral cortex neuron Trace 3J , 3K , 3N Layer 2/3 neurons barely detectable.
TS27: cortical layer III cerebral cortex neuron Trace 3J , 3K , 3N Layer 2/3 neurons barely detectable.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory