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Gene Expression Data
Assay Details
Assay
Reference: J:206632 Roberts JM, et al., Splicing factor TRA2B is required for neural progenitor survival. J Comp Neurol. 2014 Feb 1;522(2):372-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531500
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Results
Specimen 2M/O: postnatal day 0 (more )
Note: Double labeled: magenta - Bcl11b; green - Tra2b (assay MGI:7531498).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer V pyramidal neuron Strong 2M , 2O Expression in projection neurons. Higher expression in cortical layer 5 than in layer 6.
TS27: cortical layer VI pyramidal neuron Present 2M , 2N Expression in projection neurons. Higher expression in cortical layer 5 than in layer 6.
Specimen 3C: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant. Triple labeled: red - Bcl11b; blue - Bhlhe22 (assay MGI:7531501); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex pyramidal neuron Present 3C Expression specific subtypes of projection neurons.
Specimen 3D: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant. Triple labeled: red - Bcl11b; blue - Bhlhe22 (assay MGI:7531501); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cerebral cortex pyramidal neuron Weak 3D Numbers of expressing cells reduced compared to control.
Specimen 3E/F/H: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2b+ (more )
Note: Conditional mutant. Triple labeled: red - Bcl11b; blue - Bhlhe22 (assay MGI:7531501); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer V pyramidal neuron Present 3H , 3F , 3E
TS27: cortical layer VI pyramidal neuron Present 3H , 3F , 3E
Specimen 3J/K/M: postnatal day 0; Emx1tm1(cre)Krj/Emx1+, Tra2btm1.1Bwir/Tra2btm1.1Bwir (more )
Note: Conditional mutant. Triple labeled: red - Bcl11b; blue - Bhlhe22 (assay MGI:7531501); green - Tbr1 (assay MGI:7531502).
Structure Cell Type Level Pattern Image Note
TS27: cortical layer V pyramidal neuron Weak 3K , 3J , 3M Numbers of expressing cells reduced compared to control.
TS27: cortical layer VI pyramidal neuron Weak 3K , 3J , 3M Numbers of expressing cells reduced compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory