Piezo1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:333869 Nourse JL, et al., Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development. J Gen Physiol. 2022 Oct 3;154(10)
Assay type:	RNA in situ
MGI Accession ID:	MGI:7481975
Gene symbol:	Piezo1
Gene name:	piezo-type mechanosensitive ion channel component 1

Results

Specimen 2A - WT forebrain: embryonic day 10.5 (more

)
Note: Triple labeled: yellow - Piezo1; magenta - Tubb3 (assay MGI:7481980); cyan - Hoechst.

Structure	Level	Pattern	Image	Note
TS17: forebrain	Present	Punctate	2A WT Forebrain Piezo1 , 2A WT Forebrain merge	Expression spans the width of the neuroepithelium.

Specimen 2A - WT midbrain: embryonic day 10.5 (more

)
Note: Triple labeled: yellow - Piezo1; magenta - Tubb3 (assay MGI:7481980); cyan - Hoechst.

Structure	Level	Pattern	Image	Note
TS17: midbrain	Present	Punctate	2A WT Midbrain Piezo1 , 2A WT Midbrain merge	Expression spans the width of the neuroepithelium.

S1_WT merge ©

S1_WT Piezo1 ©

Specimen 2A/S1 - WT hindbrain: embryonic day 10.5 (more

)
Note: Triple labeled: yellow - Piezo1; magenta - Tubb3 (assay MGI:7481980); cyan - Hoechst.

Structure	Level	Pattern	Image	Note
TS17: hindbrain	Present	Punctate	S1_WT merge , S1_WT Piezo1 , 2A WT Hindbrain Piezo1 , 2A WT Hindbrain merge	Expression spans the width of the neuroepithelium.
TS17: brain blood vessel	Strong		2A WT Hindbrain merge , S1_WT merge , 2A WT Hindbrain Piezo1 , S1_WT Piezo1

Specimen 2A - KO midbrain: embryonic day 10.5; Piezo1^{Gt(RST343)Byg}/Piezo1^{Gt(RST343)Byg} (more

)
Note: Triple labeled: yellow - Piezo1; magenta - Tubb3 (assay MGI:7481980); cyan - Hoechst.

Structure	Level	Pattern	Image	Note
TS17: midbrain	Absent		2A KO Midbrain Piezo1 , 2A KO Midbrain merge

S1_KO merge ©

S1_KO Piezo1 ©

Specimen S1 - KO hindbrain: embryonic day 10.5; Piezo1^{Gt(RST343)Byg}/Piezo1^{Gt(RST343)Byg} (more

)
Note: Triple labeled: yellow - Piezo1; magenta - Tubb3 (assay MGI:7481980); cyan - Hoechst.

Structure	Level	Pattern	Image	Note
TS17: hindbrain	Absent		S1_KO Piezo1 , S1_KO merge

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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