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Gene Expression Data
Assay Details
Assay
Reference: J:334253 Stavely R, et al., A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development. Development. 2023 Mar 1;150(5):dev201090
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7461268
Gene symbol: Mapt
Gene name: microtubule-associated protein tau
Reporter: GFP
Antibody: anti-GFP
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 4C: postnatal; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Mapttm1(EGFP)Klt/Mapt+ (more )
Note: Conditional mutant. Triple labeled: green - Mapt reporter; blue - Elavl4 (assay MGI:7461265); red - Tubb3 (assay MGI:7461266).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present 4C merged , 4C Tau-GFP
Specimen 4D: embryonic day 11.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Mapttm1(EGFP)Klt/Mapt+ (more )
Note: Conditional mutant. Double labeled: green - Mapt reporter; red - Cre reporter.
Structure Level Pattern Image Note
TS19: embryo Present 4D
Specimen 4E: embryonic day 11.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Mapttm1(EGFP)Klt/Mapt+ (more )
Note: Conditional mutant. Double labeled: green - Mapt reporter; red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS19: gut migratory enteric neural crest cell Present Regionally restricted 4E Tau-GFP , 4E merged Expression in enteric neural crest-derived neurons (ENCDCs) limited in wavefront but strong in trailing region.
Specimen 4F: embryonic day 11.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/0, Mapttm1(EGFP)Klt/Mapt+ (more )
Note: Conditional mutant. Double labeled: green - Mapt reporter; red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS19: gut migratory enteric neural crest cell Strong Regionally restricted 4F Strong expression in enteric neural crest-derived neurons (ENCDCs) in trailing region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory