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Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449023
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin (#610153), clone 14
Detection system: Secondary antibody coupled to Alexa Fluor 594
Assay notes: Multiple Ggps1 antibodies were described, but the one used in this assay was not detailed. Anti-GGPS1 MGI:7448882 may have been used in this assay.
Results
Specimen 6A beta-Catenin E10.5 Control: embryonic day 10.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+). Double labeled: red - beta-Catenin (Ctnnb1); green - N-cadherin (Cdh2 assay MGI:7449022).
Structure Level Pattern Image Note
TS17: heart Present 6A E10.5 Control beta-Catenin , 6A E10.5 Control Merge
Specimen 6A beta-Catenin E10.5 Cre/+: embryonic day 10.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - beta-Catenin (Ctnnb1); green - N-cadherin (Cdh2 assay MGI:7449022).
Structure Level Pattern Image Note
TS17: heart Present 6A E10.5 Cre/+ beta-Catenin , 6A E10.5 Cre/+ Merge
Specimen 6A beta-Catenin E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+). Double labeled: red - beta-Catenin (Ctnnb1); green - N-cadherin (Cdh2 assay MGI:7449022).
Structure Level Pattern Image Note
TS19: heart Present 6A E11.5 Control beta-Catenin , 6A E11.5 Control Merge
Specimen 6A beta-Catenin E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - beta-Catenin (Ctnnb1); green - N-cadherin (Cdh2 assay MGI:7449022).
Structure Level Pattern Image Note
TS19: heart Present Regionally restricted 6A E11.5 Cre/+ beta-Catenin , 6A E11.5 Cre/+ Merge Expression weakened on cell-cell contacts and increased in cytoplasm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory