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Gene Expression Data
Assay Details
Assay
Reference: J:202041 Page ME, et al., The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell. 2013 Oct 3;13(4):471-82
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7443158
Gene symbol: Lrig1
Gene name: leucine-rich repeats and immunoglobulin-like domains 1
Antibody: anti-Lrig1 (AF3688)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1B/D: postnatal adult; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Back skin in telogen (resting) phase. Double labeled: red - Lrig1 protein; green - Lrig1 reporter (assay MGI:7442826).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1B , 1D Expression is seen in the junctional zone.
TS28: hair follicle isthmus Present Regionally restricted 1D , 1B Expression is seen in the upper isthmus.
TS28: sebaceous gland Present 1B , 1D
Specimen 1E: postnatal adult (more )
Note: Back skin in telogen (resting) phase. Double labeled: red - Lrig1; green - Cd34 (assay MGI:7443208).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1E Expression is seen in the junctional zone.
TS28: sebaceous gland Present 1E
Specimen 1G: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Note: Back skin in anagen (growth) phase. Double labeled: red - Lrig1 ; green - Lgr5 (assay MGI:7443207).
Structure Level Pattern Image Note
TS28: hair germ Present 1G
TS28: hair outer root sheath Present 1G
Specimen 1H: postnatal adult (more )
Note: Back skin in telogen (resting) phase. Double labeled: red - Lrig1; green - Plet1 (assay MGI:7443210).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1H Expression is seen in the junctional zone.
TS28: hair follicle isthmus Present 1H
TS28: sebaceous gland Present 1H
Specimen 1I: postnatal adult; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Back skin in telogen (resting) phase. Double labeled: red - Lrig1; green - Lgr6 (assay MGI:7443206).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1I Expression is seen in the junctional zone.
TS28: hair follicle isthmus Present 1I
TS28: sebaceous gland Present 1I
Specimen 2F: postnatal adult (more )
Note: Back skin in telogen (resting) phase. Double labeled: red - Lrig1; green - Mki67 (assay MGI:7443209).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 2F Expression is seen in the junctional zone.
TS28: sebaceous gland Present 2F
Specimen S1B: postnatal adult (more )
Note: Back epidermis. Triple labeled: red - Lrig1; green - Krt10 (assay MGI:7443213); blue - Itga6 (assay MGI:7443211).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted S1B Expression is seen in the junctional zone.
TS28: sebaceous gland Present S1B
Specimen S1C: postnatal adult; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Back epidermis. Double labeled: red - Lrig1; green - Lgr6 (assay MGI:7443206).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted S1C Expression is seen in the junctional zone.
Specimen S2A/C: postnatal adult; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Tail epidermis. Double labeled: red - Lrig1 protein; green - Lrig1 reporter (assay MGI:7442826).
Structure Level Pattern Image Note
TS28: sebaceous gland Present S2A , S2C
Specimen S2F: postnatal adult (more )
Note: Tail epidermis. Double labeled: red - Lrig1; green - Mki67 (assay MGI:7443209).
Structure Level Pattern Image Note
TS28: sebaceous gland Present S2F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory