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Gene Expression Data
Assay Details
Assay
Reference: J:202041 Page ME, et al., The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell. 2013 Oct 3;13(4):471-82
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7442826
Gene symbol: Lrig1
Gene name: leucine-rich repeats and immunoglobulin-like domains 1
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1C/D: postnatal adult; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Back skin in telogen (resting) phase. Double labeled: green - Lrig1 reporter; red - Lrig protein (assay MGI:7443158).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1C , 1D Expression is seen in the junctional zone.
TS28: sebaceous gland Present 1C , 1D
Specimen 1J: postnatal adult; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Back skin in telogen (resting) phase. Double labeled: green - Lrig1; red - Prdm1 (assay MGI:7443212).
Structure Level Pattern Image Note
TS28: sebaceous gland Present Regionally restricted 1J Expression is seen in the basal layer, not in suprabasal cells.
Specimen S2B/C: postnatal adult; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Tail epidermis. Double labeled: green - Lrig1 reporter; red - Lrig protein (assay MGI:7443158).
Structure Level Pattern Image Note
TS28: sebaceous gland Present S2B , S2C
Specimen S2D: postnatal adult; Lrig1tm1(cre/ERT2)Kjen/Lrig1+ (more )
Note: Tail epidermis. Double labeled: green - Lrig1; red - Cd34 (assay MGI:7443208).
Structure Level Pattern Image Note
TS28: sebaceous gland Present S2D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory