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Gene Expression Data
Assay Details
Assay
Reference: J:331142 Han P, et al., Cbln1 regulates axon growth and guidance in multiple neural regions. PLoS Biol. 2022 Nov;20(11):e3001853
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388457
Gene symbol: Lhx5
Gene name: LIM homeobox protein 5
Antibody: anti-Lim1/2
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S1D Lim1/2: embryonic day 11.0 (more )
Note: Double labeled: red - Lhx1 and Lhx5; green - Cbln1 (assay MGI:7388453).
Structure Cell Type Level Pattern Image Note
TS18: future spinal cord commissural neuron Present Regionally restricted S1D Lim1/2 , S1D (merged) Expression in dI2 dorsal commissural neurons.
Specimen S2D Cbln1fl/fl: embryonic day 11.5; Cbln1tm1.1Sjj/Cbln1tm1.1Sjj (more )
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord commissural neuron Present Regionally restricted S2D Cbln1fl/fl Lim1/2 Expression in dI2 dorsal commissural neurons.
Specimen S2D Wnt1-Cre: embryonic day 11.5; Cbln1tm1.1Sjj/Cbln1tm1.1Sjj, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord commissural neuron Present Regionally restricted S2D Wnt1-Cre Lim1/2 Patterning not affected for dI2 neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory