Cbln1^tm1.1Sjj
Targeted Allele Detail

Summary

• Symbol: Cbln1^tm1.1Sjj
• Name: cerebellin 1 precursor protein; targeted mutation 1.1, Sheng-Jian Ji
• MGI ID: MGI:7388239
• Gene: Cbln1 Location: Chr8:88195481-88199220 bp, - strand Genetic Position: Chr8, 42.16 cM
• Alliance: Cbln1^tm1.1Sjj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331142
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site upstream of the coding region in exon 1 and an FRT-flanked neomycin cassette with a 3 loxP site downstream of the coding region in exon 3. Flp-mediated recombination removed the selection cassette and left the coding region floxed. (J:331142)

Expression

In Mice Carrying this Mutation:

29 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cbln1 Mutation: 15 strains or lines available

References

• Original: J:331142 Han P, et al., Cbln1 regulates axon growth and guidance in multiple neural regions. PLoS Biol. 2022 Nov;20(11):e3001853
• All: 1 reference(s)