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Gene Expression Data
Assay Details
Assay
Reference: J:308866 Mase S, et al., Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis. Neurosci Res. 2021 Sep;170:122-132
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6755499
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-Eomes (Dan11mag, 50-4875-82,14-4875-80)
Detection system: Alexa Fluor 680
Results
Specimen 1A Notch1+/D Notch2+/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1+, Notch2tm3Grid/Notch2+ (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS19: telencephalon Present 1A Notch1+/D Notch2+/D merge , 1A Notch1+/D Notch2+/D Tbr2 Expression in committed neural progenitors in dorsal cortex.
Specimen 1A Notch1D/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1tm2Rko (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS19: telencephalon Present 1A Notch1D/D Tbr2 , 1A Notch1D/D merge Authors report an increase in differentiating cells.
Specimen 1A Notch2D/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS19: telencephalon Present 1A Notch2D/D merge , 1A Notch2D/D Tbr2
Specimen 1A Notch1D/D Notch2D/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1tm2Rko, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS19: telencephalon Present 1A Notch1D/D Notch2D/D Tbr2 , 1A Notch1D/D Notch2D/D merge Effects were more drastic than those of Notch1 single knockout.
Specimen 1B Notch1+/D Notch2+/D: embryonic day 13.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1+, Notch2tm3Grid/Notch2+ (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS21: cerebral cortex Present 1B Notch1+/D Notch2+/D Tbr2 , 1B Notch1+/D Notch2+/D merge Expression in committed neural progenitors in dorsal cortex.
Specimen 1B Notch1D/D: embryonic day 13.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1tm2Rko (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS21: cerebral cortex Present 1B Notch1D/D Tbr2 , 1B Notch1D/D merge Authors report an increase in differentiating cells.
Specimen 1B Notch2D/D: embryonic day 13.5; Emx1tm1(cre)Yql/Emx1+, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS21: cerebral cortex Present 1B Notch2D/D Tbr2 , 1B Notch2D/D merge
Specimen 1B Notch1D/D Notch2D/D: embryonic day 13.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1tm2Rko, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Triple labeled: magenta - Tbr2 (Eomes); green - Sox2 (assay MGI:6755498); blue - DAPI.
Structure Level Pattern Image Note
TS21: cerebral cortex Present 1B Notch1D/D Notch2D/D Tbr2 , 1B Notch1D/D Notch2D/D merge Effects were more drastic than those of Notch1 single knockout.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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