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Gene Expression Data
Assay Details
Assay
Reference: J:290712 Ishiguro KI, et al., MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6721111
Gene symbol: Dmc1
Gene name: DNA meiotic recombinase 1
Antibody: anti-Dmc1 (H-100; sc-22768)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4B WT: postnatal week 8 (more )
Note: Triple labeled: green - Dmc1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 4B WT (merge) , 4B WT Dmc1
Specimen 4B Meiosin KO: postnatal day 8; Meiosinem1Keish/Meiosinem1Keish (more )
Note: Triple labeled: green - Dmc1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Ambiguous Regionally restricted 4B Meiosin KO (merge) , 4B Meiosin KO Dmc1 Expression rarely observed in Meiosin KO preleptotene-like cells.
Specimen 4B Stra8 KO: postnatal day 8; Stra8em4Keish/Stra8em4Keish (more )
Note: Triple labeled: green - Dmc1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 4B Stra8 KO (merge) , 4B Stra8 KO Dmc1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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