About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:127471 Wang S, et al., Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse. Mech Dev. 2007 Nov-Dec;124(11-12):898-910
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6449809
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-glucagon MGI:6449774 may have been used in this assay.
Results
Specimen 1B1: embryonic day 9.0 (more )
Note: Triple labeled: green - Gcg; red - Myt1 (assay MGI:6449800); blue - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS14: foregut-midgut junction Present Regionally restricted 1B1 Expression in prospective pancreas.
Specimen 1B2: embryonic day 10.5 (more )
Note: Triple labeled: green - Gcg; red - Myt1 (assay MGI:6449800); blue - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 1B2
Specimen 1B3: embryonic day 15.5 (more )
Note: Double labeled: green - Gcg; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present 1B3
Specimen 1B4: postnatal week 12 (more )
Note: Double labeled: green - Gcg; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 1B4
Specimen 1B4 inset: postnatal week 12 (more )
Note: Double labeled: green - Gcg; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 1B4 inset
Specimen 6A: postnatal adult; Myt1tm1Ggu/Myt1tm1.1Ggu, Tg(Pdx1-cre)89.1Dam/? (more )
Note: Conditional mutant. Triple labeled: green - Gcg; blue - Mafa (assay MGI:6449813); red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted 6A glc , 6A merge Expression in cells that are not mature beta cells.
Specimen 6C: postnatal adult; Myt1tm1Ggu/Myt1tm1.1Ggu, Tg(Pdx1-cre)89.1Dam/? (more )
Note: Conditional mutant. Triple labeled: green - Gcg; blue - Mafb (assay MGI:6449814); red - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted 6C glc , 6C merge Expression in cells that are not mature beta cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory