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Gene Expression Data
Assay Details
Assay
Reference: J:134435 Anselme I, et al., Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes. Dev Biol. 2007 Apr 1;304(1):208-20
Assay type: RNA in situ
MGI Accession ID: MGI:6382586
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2H: embryonic day 8.0 (more )
Note: 7 somites.
Structure Level Pattern Image Note
TS12: future prosencephalon Present Widespread 2H Expression in whole forebrain region up to forebrain-midbrain boundary.
TS12: future midbrain Absent 2H
Specimen 2J: embryonic day 8.0 (more )
Note: 7 somites. Double labeled: purple - Pax6; red - Otx2 (assay MGI:6382587).
Structure Level Pattern Image Note
TS12: future prosencephalon Present Widespread 2J Expression in whole forebrain region up to forebrain-midbrain boundary.
TS12: future midbrain Absent 2J
Specimen 2N: embryonic day 8.5 (more )
Note: 9 somites. Also stained for Wnt1 (assay MGI:6382589); both purple.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 2N
TS13: future midbrain Absent 2N
Specimen 2R: embryonic day 9.5 (more )
Note: Double labeled: purple - Pax6; red - Otx2 (assay MGI:6382587).
Structure Level Pattern Image Note
TS15: future forebrain Present 2R
TS15: future midbrain Absent 2R
Specimen 3K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 3K Expression restricted to dorsal part of telencephalon (pallium).
TS15: diencephalon Present Regionally restricted 3K Expression in dorsal diencephalon.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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