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Gene Expression Data
Assay Details
Assay
Reference: J:124867 Wrobel CN, et al., Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. Dev Biol. 2007 Sep 15;309(2):285-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6376109
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti PAX6 (DSHB)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 4A WT: embryonic day 14.5 (more )
Note: Double labeled: red - Pax6; green - Eomes (assay MGI:6376110).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Weak 4A WT
Specimen 4A: embryonic day 14.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Pax6; green - Eomes (assay MGI:6376110).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 4A deltaEx3
TS22: cerebral cortex Present 4A deltaEx3 There is an expansion in expression in this mutant compared to controls.
Specimen 4B WT: embryonic day 17.5 (more )
Note: Double labeled: red - Pax6; green - Eomes (assay MGI:6376110).
Structure Level Pattern Image Note
TS25: cerebral cortex ventricular layer Present 4B WT
Specimen 4B: embryonic day 17.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Pax6; green - Eomes (assay MGI:6376110).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 4B deltaEx3 In this mutant there is widespread disorganized expression throughout the developing cortex.
TS25: cerebral cortex ventricular layer Present 4B deltaEx3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory