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Gene Expression Data
Assay Details
Assay
Reference: J:203015 Panayiotou E, et al., Pax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice. Gene Expr Patterns. 2013 Dec;13(8):328-34
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6360698
Gene symbol: Gt(ROSA)26Sor
Gene name: gene trap ROSA 26, Philippe Soriano
Reporter: lacZ
Antibody: anti-GFP (Invitrogen)
Assay notes: Two antibodies were described MGI:5014292 and MGI:6356546; either could have been used in this assay.
Results
Specimen 2A: embryonic day 14.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Dbx1-icre)1Wdr/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 2C , 2A Expression was detected in the Dbx1 lineage (labeling dorsalI6-, dI5-, p0- and p1-derived cells).
Specimen 2D: embryonic day 14.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Foxn4-icre)1Smal/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 2D , 2F Expression was detected in the Foxn4 lineage (labeling p2-derived neurons).
Specimen 2G: embryonic day 14.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Olig2tm1.1(cre)Wdr/Olig2+ (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 2G , 2I Expression was detected in the Olig2 lineage (labeling p3-, pMN- and very few p2-derived cells).
Specimen S1A: embryonic day 13.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Foxn4-icre)1Smal/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted S1C , S1A The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen S1D: embryonic day 15.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Foxn4-icre)1Smal/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS23: spinal cord Present Regionally restricted S1D , S1F The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen S1G: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Foxn4-icre)1Smal/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS25: spinal cord Present Regionally restricted S1I , S1G The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen S1J: postnatal day 4; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Foxn4-icre)1Smal/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted S1L , S1J The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen S1M: postnatal day 25; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Foxn4-icre)1Smal/0 (more )
Note: Conditional mutant. Double labeled: green - Gt(ROSA)26Sor reporter; red - Pax6 (assay MGI:6360666). Specimen was fixed in MEMFA or 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted S1O , S1M The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true into adulthood.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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