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Gene Expression Data
Assay Details
Assay
Reference: J:226703 Shimada M, et al., Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability. EMBO J. 2015 Oct 1;34(19):2465-80
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6358705
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: anti-CTIP2 [25B6] (ab18465)
Detection system: fluorescein
Results
Specimen 3B Control Ctip2: postnatal day 0 (more )
Note: Double labeled: green - Ctip2 (Bcl11b); red - Satb2 (assay MGI:6358701).
Structure Level Pattern Image Note
TS27: neocortex Strong Regionally restricted 3B Control Ctip2 , 3B Control Merge

Specimen 3B PNKP Nes-Cre Ctip2: postnatal day 0; Pnkptm1.1Pmc/Pnkptm1.1Pmc, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Ctip2 (Bcl11b); red - Satb2 (assay MGI:6358701).
Structure Level Pattern Image Note
TS27: neocortex Weak Regionally restricted 3B Pnkp Nes-Cre Merge , 3B Pnkp Nes-Cre Ctip2

Specimen 3B (Pnkp;p53) Nes-Cre Ctip2: postnatal day 0; Pnkptm1.1Pmc/Pnkptm1.1Pmc, Tg(Nes-cre)1Kln/0, Trp53tm1Tyj/Trp53tm1Tyj (more )
Note: Conditional mutant. Double labeled: green - Ctip2 (Bcl11b); red - Satb2 (assay MGI:6358701).
Structure Level Pattern Image Note
TS27: neocortex Present Regionally restricted 3B (Pnkp;p53) Nes-Cre Ctip2 , 3B (Pnkp;p53) Nes-Cre Merge Authors report recovery of neuronal numbers and a more ordered cortical lamination.

Specimen 3B (Pnkp;Atk) Nes-Cre Ctip2: postnatal day 0; Atmtm2Pmc/Atmtm2Pmc, Pnkptm1.1Pmc/Pnkptm1.1Pmc, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Ctip2 (Bcl11b); red - Satb2 (assay MGI:6358701).
Structure Level Pattern Image Note
TS27: neocortex Weak Regionally restricted 3B (Pnkp;Atm) Nes-Cre Merge , 3B (Pnkp;Atm) Nes-Cre Ctip2


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory