Itga9 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:271100 Shen B, et al., Genetic dissection of tie pathway in mouse lymphatic maturation and valve development. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1221-30
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6314708
Gene symbol:	Itga9
Gene name:	integrin alpha 9

Antibody:

Results

Specimen 3D ICD/ICD Integrin-a9: embryonic day 18.5; Tie1^tm1.1Yuhe/Tie1^tm1.1Yuhe, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Double labeled: red - Itga9; green - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: lymphatic system	Present	Regionally restricted	3D ICD/ICD Overlay , 3D ICD/ICD Integrin-a9	Authors report no formation of collecting lymphatic vessels and valves in homozygous mutant mice.

Specimen 3D +/ICD Integrin-a9: embryonic day 18.5; Tie1^tm1.1Yuhe/Tie1⁺, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Double labeled: red - Itga9; green - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: back skin	Present	Regionally restricted	3D +/ICD Integrin-a9 , 3D +/ICD Overlay	Expression in lymphatic endothelial cells.

Specimen 3D +/+ Integrin-a9: embryonic day 18.5 (more

)
Note: Double labeled: red - Itga9; green - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: back skin	Present	Regionally restricted	3D +/+ Integrin-a9 , 3D +/+ Overlay	Expression in lymphatic endothelial cells.

Specimen 4C ICD/ICD Integrin-a9: embryonic day 18.5; Tie1^tm1.1Yuhe/Tie1^tm1.1Yuhe, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Triple labeled: green - Itga9; green - Prox1 (assay MGI:6314707); red - Acta2 (assay MGI:6314700).

Structure	Level	Pattern	Image	Note
TS26: lymphatic system	Present	Regionally restricted	4C ICD/ICD Integrin-a9	Authors report no formation of lymphatic valves in mesentery of homozygous mutants.

Specimen 4C +/ICD Integrin-a9: embryonic day 18.5; Tie1^tm1.1Yuhe/Tie1⁺, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Triple labeled: green - Itga9; green - Prox1 (assay MGI:6314707); red - Acta2 (assay MGI:6314700).

Structure	Level	Pattern	Image	Note
TS26: gut mesentery	Present	Regionally restricted	4C +/ICD Overlay , 4C +/ICD Integrin-a9

Specimen 4C +/+ Integrin-a9: embryonic day 18.5 (more

)
Note: Triple labeled: green - Itga9; green - Prox1 (assay MGI:6314707); red - Acta2 (assay MGI:6314700).

Structure	Level	Pattern	Image	Note
TS26: gut mesentery	Present	Regionally restricted	4C +/+ Overlay , 4C +/+ Integrin-a9

Specimen 7G Ang2-/- Integrin-a9: embryonic day 18.5; Angpt2^tm1.1Yuhe/Angpt2^tm1.1Yuhe, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Double labeled: green - Itga9; red - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: lymphatic vessel	Present	Regionally restricted	7G Ang2-/- Integrin-a9 , 7G Ang2-/- Overlay	Authors report no formation of collecting lymphatic vessels and valves in homozygous mutant mice.

Specimen 7G Ang2+/- Integrin-a9: embryonic day 18.5; Angpt2^tm1.1Yuhe/Angpt2⁺, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Double labeled: green - Itga9; red - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: lymphatic vessel	Present		7G Ang2+/- Overlay , 7G Ang2+/- Integrin-a9

Specimen S3B Ang2-/- Integrin-a9: embryonic day 18.5; Angpt2^tm1.1Yuhe/Angpt2^tm1.1Yuhe, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Double labeled: red - Itga9; green - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: lymphatic system	Present	Regionally restricted	S3B Ang2-/- Integrin-a9 , S3B Ang2-/- Overlay	Authors report no formation of lymphatic valves in mesentery of homozygous mutant mice.

Specimen S3B Ang2+/- Integrin-a9: embryonic day 18.5; Angpt2^tm1.1Yuhe/Angpt2⁺, Tg(EIIa-cre)C5379Lmgd/0 (more

)
Note: Conditional mutant. Double labeled: red - Itga9; green - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: gut mesentery	Present		S3B Ang2+/- Integrin-a9 , S3B Ang2+/- Overlay

Specimen S3B Ang2+/+ Integrin-a9: embryonic day 18.5 (more

)
Note: Double labeled: red - Itga9; green - Prox1 (assay MGI:6314707).

Structure	Level	Pattern	Image	Note
TS26: gut mesentery	Present		S3B Ang2+/+ Overlay , S3B Ang2+/+ Integrin-a9

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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