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Gene Expression Data
Assay Details
Assay
Reference: J:264159 Zurner M, et al., Analyses of the spatiotemporal expression and subcellular localization of liprin-alpha proteins. J Comp Neurol. 2011 Oct 15;519(15):3019-39
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6256574
Gene symbol: Ppfia1
Gene name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Antibody: Liprin-alpha1 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Punctate 5A
TS28: cerebellum molecular layer Present 5A
TS28: cerebellum Purkinje cell layer Absent 5A
Specimen 6A: postnatal week 7-10 (more )
Note: Double labeled: green - Ppfia1; purple - Syn1 (assay MGI:6256575).
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Punctate 6A , 6C
TS28: cerebellum molecular layer Strong 6A , 6C
TS28: cerebellum Purkinje cell layer Absent 6C , 6A
Specimen 7A: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Weak 7A
TS28: hippocampus pyramidal cell layer Weak 7A
TS28: blood vessel endothelium Present 7A
Specimen 8A: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong 8A
TS28: main olfactory bulb olfactory nerve layer Strong 8A
TS28: main olfactory bulb external plexiform layer Absent 8A
Specimen 10A: postnatal week 10 (more )
Note: Double labeled: green - Ppfia1; purple - Ctbp2 (assay MGI:6256576).
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 10A , 10C
TS28: photoreceptor layer outer segment Present 10A , 10C
TS28: retina inner plexiform layer Present 10A , 10C
TS28: retina outer plexiform layer Present Regionally restricted 10A , 10C Expression is oriented toward the inner retina.
TS28: neural retina Present Regionally restricted 10A , 10C Expression is in a cell spanning the whole inner retina from the ganglion cell layer to the outer plexiform layer.
Specimen not shown: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: brainstem Present Uniform
TS28: cerebral cortex Present Uniform
TS28: corpus striatum Weak
TS28: thalamus Weak
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory