About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:233088 Frame JM, et al., Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity. Stem Cells. 2016 Feb;34(2):431-44
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6201396
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Antibody: anti-Flk-1
Detection system: Secondary antibody
Assay notes: Fixative was either acetone or 2% formaldehyde.
Results
Specimen 2D top: embryonic day 9.5 (more )
Note: 22 somite pairs. Double labeled: red - Kdr; green - Kit (assay MGI:6201387).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 2D top Expression is in the endothelium.
Specimen 2D second: embryonic day 9.5 (more )
Note: 22 somite pairs. Double labeled: red - Kdr; green - Kit (assay MGI:6201387).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 2D second Expression is in the endothelium.
Specimen 2D third: embryonic day 9.5 (more )
Note: 22 somite pairs. Double labeled: red - Kdr; green - Kit (assay MGI:6201387).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 2D third Expression is in the endothelium.
Specimen 2D fourth: embryonic day 9.5 (more )
Note: 22 somite pairs. Double labeled: red - Kdr; green - Kit (assay MGI:6201387).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 2D fourth Expression is in the endothelium.
Specimen 5F: embryonic day 9.5 (more )
Note: 20 somite pairs. Flat mount. Triple labeled: red - Kdr; green - Kit (assay MGI:6201387); blue - Runx1 (assay MGI:6201389).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 5F Expression is in the endothelium.
Specimen S1B Runx1+/-: embryonic day 9.5; Runx1tm1Dow/Runx1+ (more )
Note: 23 somite pairs. Double labeled: red - Kdr; green - Kit (assay MGI:6201387).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present S1B top Expression is in the endothelium.
Specimen S1B Runx1-/-: embryonic day 9.5; Runx1tm1Dow/Runx1tm1Dow (more )
Note: 23 somite pairs. Double labeled: red - Kdr; green - Kit (assay MGI:6201387).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted S1B bottom Expression is in the endothelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory