S2bpcox16 MGI Mouse Gene Detail - MGI:5141963 - synaptojanin 2 binding protein Cox16 readthrough

S2bpcox16 Gene Detail

Sequence Map

Chr12:81405634-81579679 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

For selected strains:

Vertebrate Orthology Source

Alliance of Genome Resources

MGI Vertebrate Homology

S2bpcox16 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SYNJ2BP
Gene Tree

S2bpcox16

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Comparison Matrix

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			Length	Strain/Species	Flank
genomic	ENSMUSG00000021139	Ensembl Gene Model \| MGI Sequence Detail	174046	C57BL/6J	± kb
transcript	ENSMUST00000166664	Ensembl \| MGI Sequence Detail	2284	Not Applicable
polypeptide	ENSMUSP00000131728	Ensembl \| MGI Sequence Detail	182	Not Applicable

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MGI:7481234

Summaries

All 14

Phenotypes 6
Earliest

J:76839 Matsuzaki T, et al., Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway. J Biol Chem. 2002 May 24;277(21):19008-18
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for S2bpcox16:

(View these features in JBrowse)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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