About   Help   FAQ
Spmip2 Gene Detail
Summary
  • Symbol
    Spmip2
  • Name
    sperm microtubule inner protein 2
  • Synonyms
    Gm17359
Location &
Maps
more
  • Sequence Map
    Chr3:79243968-79371436 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 34.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3754 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4936993
 protein coding gene Chr3:79243937-79371436 (+)
129S1/SvImJ ENSMUSG00200018748
 protein coding gene Chr3:76024082-76152034 (+)
A/J ENSMUSG00195011316
 protein coding gene Chr3:76086843-76214913 (+)
AKR/J ENSMUSG00220001475
 protein coding gene Chr3:76099972-76228184 (+)
BALB/cJ ENSMUSG00180001790
 protein coding gene Chr3:76178739-76306939 (+)
C3H/HeJ ENSMUSG00175007212
 protein coding gene Chr3:76025009-76153064 (+)
C57BL/6NJ ENSMUSG00215001981
 protein coding gene Chr3:76476048-76603794 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025083
 protein coding gene Chr3:72089107-72219422 (+)
CAST/EiJ ENSTCUG00005001651
 protein coding gene Chr3:75583555-75712418 (+)
CBA/J ENSMUSG00210025420
 protein coding gene Chr3:76107447-76235501 (+)
DBA/2J ENSMUSG00185012474
 protein coding gene Chr3:76263486-76391697 (+)
FVB/NJ ENSMUSG00205006094
 protein coding gene Chr3:75120171-75248230 (+)
JF1/MsJ ENSUMUG00000000817
 protein coding gene Chr3:75842589-75970893 (+)
LP/J ENSMUSG00230008411
 protein coding gene Chr3:78278761-78406699 (+)
NOD/ShiLtJ ENSMUSG00190002513
 protein coding gene Chr3:76597987-76726016 (+)
NZO/HlLtJ ENSMUSG00225004403
 protein coding gene Chr3:80993795-81121890 (+)
PWK/PhJ ENSLUMG00010006241
 protein coding gene Chr3:75918335-76046608 (+)
SPRET/EiJ ENSMSPG00010016421
 protein coding gene Chr3:76654235-76779646 (+)
WSB/EiJ ENSIUOG00005002840
 protein coding gene Chr3:76509782-76637086 (+)



Homology
more
  • Human Ortholog
    SPMIP2, sperm microtubule inner protein 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMIP2, sperm microtubule inner protein 2
  • Synonyms
    C4orf45
  • Links
    NCBI Gene ID: 152940
    UniProt: Q96LM5

  • Chr Location
    4q32.1; chr4:158893134-159082885 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal fertility.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000091685 Ensembl Gene Model | MGI Sequence Detail 127469 C57BL/6J ±  kb
    transcript ENSMUST00000199658 Ensembl | MGI Sequence Detail 1819 Not Applicable  
    polypeptide ENSMUSP00000142709 Ensembl | MGI Sequence Detail 487 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR027814 Protein of unknown function DUF4562
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3
    Other
    Accession IDs
    less
    MGI:7470723
    References
    more
    • Summaries
      All 24
      Developmental Gene Expression 1
      Diseases 1
      Phenotypes 14
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:385300 Chang HY, et al., Mouse genome engineering uncovers 18 genes dispensable for male reproduction. Andrology. 2026 Mar;14(3):833-846
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory