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Ighv2-2 Gene Detail
Summary
  • Symbol
    Ighv2-2
  • Name
    immunoglobulin heavy variable 2-2
  • Synonyms
    Gm16970
Location &
Maps
more
  • Sequence Map
    Chr12:113551887-113552320 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.13 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439894
gene segment Chr12:113551887-113552322 (-)
129S1/SvImJ ENSMUSG00200029939
gene segment Chr12:105355201-105355636 (-)
A/J ENSMUSG00195048766
gene segment Chr12:107860344-107860779 (-)
A/J ENSMUSG00195051206
gene segment Chr12:108183175-108183609 (-)
AKR/J ENSMUSG00220039643
gene segment Chr12:105787143-105787578 (-)
BALB/cJ ENSMUSG00180051143
gene segment Chr12:107123816-107124251 (-)
C3H/HeJ ENSMUSG00175050118
gene segment Chr12:109713624-109714059 (-)
C57BL/6NJ ENSMUSG00215050187
gene segment Chr12:106376028-106376463 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005043646
gene segment Chr12:106033474-106033909 (-)
CBA/J ENSMUSG00210040734
gene segment Chr12:106770051-106770486 (-)
DBA/2J ENSMUSG00185030837
gene segment Chr12:108585930-108586365 (-)
FVB/NJ ENSMUSG00205047282
gene segment Chr12:105799593-105800028 (-)
JF1/MsJ ENSUMUG00000034217
gene segment Chr12:113346926-113347361 (-)
LP/J ENSMUSG00230048230
gene segment Chr12:115604012-115604447 (-)
NOD/ShiLtJ ENSMUSG00190027862
gene segment Chr12:105187107-105187542 (-)
NZO/HlLtJ ENSMUSG00225044320
gene segment Chr12:117365645-117366080 (-)
NZO/HlLtJ ENSMUSG00225044935
gene segment Chr12:117655084-117677685 (-)
PWK/PhJ ENSLUMG00010051538
gene segment Chr12:106842484-106842919 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005041647
gene segment Chr12:106067889-106068324 (-)



Homology
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Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 777686 NCBI Gene Model | MGI Sequence Detail 434 C57BL/6J ±  kb
polypeptide A0A075B5P8 UniProt | EBI | MGI Sequence Detail 116 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 10
    Gene Ontology 1
  • Earliest
    J:6654 Kataoka T, et al., The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse. J Biol Chem. 1982 Jan 10;257(1):277-85
  • Latest
    J:129910 Johnston CM, et al., Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region. J Immunol. 2006 Apr 1;176(7):4221-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/15/2026
MGI 6.29
The Jackson Laboratory