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Ighv3-6 Gene Detail
Summary
  • Symbol
    Ighv3-6
  • Name
    immunoglobulin heavy variable 3-6
  • Synonyms
    Gm16932
Location &
Maps
more
  • Sequence Map
    Chr12:114251772-114252067 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    109 from dbSNP Build 142
  • Strain Annotations
    24
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439856
 gene segment Chr12:114251772-114252202 (-)
129S1/SvImJ ENSMUSG00200030685
 gene segment Chr12:105999824-106000254 (-)
129S1/SvImJ ENSMUSG00200026501
 protein coding gene Chr12:105999824-106000295 (-)
A/J ENSMUSG00195043737
 protein coding gene Chr12:108762670-108763141 (-)
A/J ENSMUSG00195050949
 gene segment Chr12:108762670-108763100 (-)
AKR/J ENSMUSG00220036211
 gene segment Chr12:106380020-106380450 (-)
BALB/cJ ENSMUSG00180052937
 gene segment Chr12:108231930-108232360 (-)
BALB/cJ ENSMUSG00180046594
 protein coding gene Chr12:108231930-108232401 (-)
C3H/HeJ ENSMUSG00175042793
 gene segment Chr12:110369827-110370257 (-)
C3H/HeJ ENSMUSG00175036807
 protein coding gene Chr12:110369827-110370298 (-)
C57BL/6NJ ENSMUSG00215050876
 gene segment Chr12:107041339-107041769 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0000043
 gene segment Chr12:108843916-108844346 (-)
CAST/EiJ ENSTCUG00005041885
 gene segment Chr12:107253390-107253820 (-)
CBA/J ENSMUSG00210029526
 protein coding gene Chr12:107446322-107446793 (-)
CBA/J ENSMUSG00210036727
 gene segment Chr12:107446322-107446752 (-)
DBA/2J ENSMUSG00185032941
 gene segment Chr12:109419111-109419541 (-)
FVB/NJ ENSMUSG00205022709
 protein coding gene Chr12:106506948-106507418 (-)
JF1/MsJ ENSUMUG00000024600
 gene segment Chr12:114057594-114058023 (-)
LP/J ENSMUSG00230047695
 gene segment Chr12:116304259-116304689 (-)
NOD/ShiLtJ ENSMUSG00190031786
 gene segment Chr12:105887378-105887808 (-)
NZO/HlLtJ ENSMUSG00225043214
 gene segment Chr12:118187502-118187932 (-)
PWK/PhJ ENSLUMG00010049613
 gene segment Chr12:107731517-107731946 (-)
SPRET/EiJ ENSMSPG00010024914
 gene segment Chr12:110453019-110453449 (-)
WSB/EiJ ENSIUOG00005038582
 gene segment Chr12:106895052-106895482 (-)



Homology
more
  • Human Ortholog
    IGHV4-28, immunoglobulin heavy variable 4-28
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV4-28, immunoglobulin heavy variable 4-28
  • Synonyms
    IGHV428, VH
  • Links
    NCBI Gene ID: 28400
    UniProt: A0A0C4DH34

  • Chr Location
    14q32.33; chr14:106324254-106324760 (-)  GRCh38
  • Human Ortholog
    IGHV4-30-2, immunoglobulin heavy variable 4-30-2
  • Synonyms
    IGHV4-3, IGHV4302
  • Links
    NCBI Gene ID: 28398

  • Chr Location
    14q32.33; chr14:106349283-106349720 (-)  GRCh38
  • Human Ortholog
    IGHV4-30-4, immunoglobulin heavy variable 4-30-4
  • Synonyms
    IGHV4-3, IGHV4304
  • Links
    NCBI Gene ID: 28397
    UniProt: P0DP06

  • Chr Location
    14q32.33
  • Human Ortholog
    IGHV4-31, immunoglobulin heavy variable 4-31
  • Synonyms
    IGHV431
  • Links
    NCBI Gene ID: 28396
    UniProt: P0DP07

  • Chr Location
    14q32.33; chr14:106349283-106349792 (-)  GRCh38
  • Human Ortholog
    IGHV4-34, immunoglobulin heavy variable 4-34
  • Synonyms
    IGHV434, VH
  • Links
    NCBI Gene ID: 28395
    UniProt: P06331

  • Chr Location
    14q32.33; chr14:106373661-106374145 (-)  GRCh38
  • Human Ortholog
    IGHV4-38-2, immunoglobulin heavy variable 4-38-2
  • Synonyms
    IGHV4-B, IGHV4B
  • Links
    NCBI Gene ID: 28389
    UniProt: P0DP08

  • Chr Location
    14q32.33
  • Human Ortholog
    IGHV4-39, immunoglobulin heavy variable 4-39
  • Synonyms
    IGHV439, VH
  • Links
    NCBI Gene ID: 28394
    UniProt: P01824

  • Chr Location
    14q32.33; chr14:106421709-106422218 (-)  GRCh38
  • Human Ortholog
    IGHV4-4, immunoglobulin heavy variable 4-4
  • Synonyms
    IGHV44, VH
  • Links
    NCBI Gene ID: 28401
    UniProt: A0A075B6R2

  • Chr Location
    14q32.33; chr14:106011922-106012420 (-)  GRCh38
  • Human Ortholog
    IGHV4-59, immunoglobulin heavy variable 4-59
  • Synonyms
    IGHV459, VH
  • Links
    NCBI Gene ID: 28392
    UniProt: P01825

  • Chr Location
    14q32.33; chr14:106627249-106627825 (-)  GRCh38
  • Human Ortholog
    IGHV4-61, immunoglobulin heavy variable 4-61
  • Synonyms
    IGHV461, VH
  • Links
    NCBI Gene ID: 28391
    UniProt: A0A0C4DH41

  • Chr Location
    14q32.33; chr14:106639119-106639657 (-)  GRCh38
  • Human Ortholog
    IGHV4OR15-8, immunoglobulin heavy variable 4/OR15-8 (non-functional)
  • Synonyms
    IGHV4OR158, VSIG6
  • Links
    NCBI Gene ID: 28317

  • Chr Location
    15q11.2; chr15:22184967-22185402 (-)  GRCh38
  • Human Ortholog
    IGHV6-1, immunoglobulin heavy variable 6-1
  • Synonyms
    IGHV61, VH
  • Links
    NCBI Gene ID: 28385
    UniProt: A0A0B4J1U7

  • Chr Location
    14q32.33; chr14:105939754-105940253 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
  • All Sequences
    31
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 780829 NCBI Gene Model | MGI Sequence Detail 296 C57BL/6J ±  kb
transcript X03378 GenBank | ENA | DDBJ | MGI Sequence Detail 357 Not Specified  
polypeptide P18531 UniProt | EBI | MGI Sequence Detail 116 Not Applicable  
For the selected sequence
Protein
Information
less
References
more
  • Summaries
    All 10
    Gene Ontology 1
  • Earliest
    J:38539 Rinfret A, et al., Cloning, sequencing and expression of the rearranged MOPC 315 VH gene segment. Mol Immunol. 1989 Apr;26(4):431-4
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory