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Defb52 Gene Detail
Summary
  • Symbol
    Defb52
  • Name
    defensin beta 52
  • Synonyms
    Gm15056
Location &
Maps
more
  • Sequence Map
    Chr8:21390622-21392472 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 10.35 cM
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3705859
 protein coding gene Chr8:21390622-21392643 (-)
129S1/SvImJ ENSMUSG00200030837
 protein coding gene Chr8:16520850-16522871 (-)
A/J ENSMUSG00195039264
 protein coding gene Chr8:17060289-17062310 (-)
AKR/J ENSMUSG00220028452
 protein coding gene Chr8:17199282-17201303 (-)
BALB/cJ no annotation
C3H/HeJ ENSMUSG00175037552
 protein coding gene Chr8:16741613-16743634 (-)
C57BL/6NJ ENSMUSG00215014051
 protein coding gene Chr8:16715703-16717724 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030878
 protein coding gene Chr8:15447308-15449159 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210040034
 protein coding gene Chr8:16600917-16602938 (-)
DBA/2J ENSMUSG00185038858
 protein coding gene Chr8:22403829-22405850 (-)
FVB/NJ ENSMUSG00205026452
 protein coding gene Chr8:16314265-16316286 (-)
JF1/MsJ ENSUMUG00000012898
 protein coding gene Chr8:24583921-24585941 (-)
LP/J ENSMUSG00230011396
 protein coding gene Chr8:26302922-26304943 (-)
NOD/ShiLtJ ENSMUSG00190031876
 protein coding gene Chr8:16736844-16738865 (-)
NZO/HlLtJ ENSMUSG00225041553
 protein coding gene Chr8:29654972-29656993 (-)
PWK/PhJ ENSLUMG00010026722
 protein coding gene Chr8:16991350-16993370 (-)
SPRET/EiJ ENSMSPG00010013849
 protein coding gene Chr8:17048695-17050721 (-)
WSB/EiJ ENSIUOG00005020808
 protein coding gene Chr8:17222545-17224566 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100504014 NCBI Gene Model | MGI Sequence Detail 1851 C57BL/6J ±  kb
transcript NM_001177471 RefSeq | MGI Sequence Detail 797 C57BL/6  
polypeptide NP_001170942 RefSeq | MGI Sequence Detail 88 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
Other
Accession IDs
less
MGI:8352885
References
more
  • Summaries
    All 10
    Phenotypes 1
  • Earliest
    J:101568 Patil AA, et al., Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiol Genomics. 2005 Sep 21;23(1):5-17
  • Latest
    J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory