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Krtap4-8 Gene Detail
Summary
  • Symbol
    Krtap4-8
  • Name
    keratin associated protein 4-8
  • Synonyms
    OTTMUSG00000002541
Location &
Maps
more
  • Sequence Map
    Chr11:99670840-99671469 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.12 cM
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3652306
 protein coding gene Chr11:99670548-99671530 (-)
129S1/SvImJ ENSMUSG00200051153
 protein coding gene Chr11:96934927-96935909 (-)
A/J ENSMUSG00195047848
 protein coding gene Chr11:96636914-96637896 (-)
AKR/J ENSMUSG00220044555
 protein coding gene Chr11:96896986-96897968 (-)
BALB/cJ ENSMUSG00180044772
 protein coding gene Chr11:97012739-97013721 (-)
C3H/HeJ ENSMUSG00175050482
 protein coding gene Chr11:96908474-96909456 (-)
C57BL/6NJ ENSMUSG00215052950
 protein coding gene Chr11:96489439-96490421 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017139
 protein coding gene Chr11:95676803-95695930 (-)
CAST/EiJ ENSTCUG00005049958
 protein coding gene Chr11:96434445-96435469 (-)
CBA/J ENSMUSG00210051671
 protein coding gene Chr11:96646087-96647069 (-)
DBA/2J ENSMUSG00185051190
 protein coding gene Chr11:96958362-96959344 (-)
FVB/NJ ENSMUSG00205028026
 protein coding gene Chr11:96824239-96825221 (-)
JF1/MsJ ENSUMUG00000040759
 protein coding gene Chr11:97250597-97251624 (-)
LP/J ENSMUSG00230050735
 protein coding gene Chr11:98011170-98012152 (-)
NOD/ShiLtJ ENSMUSG00190038982
 protein coding gene Chr11:96993242-96994224 (-)
NZO/HlLtJ ENSMUSG00225050096
 protein coding gene Chr11:100069092-100070074 (-)
PWK/PhJ ENSLUMG00010046885
 protein coding gene Chr11:96808179-96809206 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005046979
 protein coding gene Chr11:96769310-96770292 (-)



Homology
more
  • Human Ortholog
    KRTAP4-11, keratin associated protein 4-11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-11, keratin associated protein 4-11
  • Synonyms
    KAP4.11, KAP4.14, KRTAP4-14, KRTAP4.14
  • Links
    NCBI Gene ID: 653240
    UniProt: Q9BYQ6

  • Chr Location
    17q21.2; chr17:41117181-41118373 (-)  GRCh38
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Synonyms
    KAP4.3
  • Links
    NCBI Gene ID: 85290
    UniProt: Q9BYR4

  • Chr Location
    17q21.2; chr17:41167231-41168221 (-)  GRCh38
  • Human Ortholog
    KRTAP4-5, keratin associated protein 4-5
  • Synonyms
    KAP4.5, KRTAP4.5
  • Links
    NCBI Gene ID: 85289
    UniProt: Q9BYR2

  • Chr Location
    17q21.2; chr17:41148924-41149825 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 665992 NCBI Gene Model | MGI Sequence Detail 630 C57BL/6J ±  kb
transcript NM_001085547 RefSeq | MGI Sequence Detail 630 Not Specified  
polypeptide NP_001079016 RefSeq | MGI Sequence Detail 209 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory