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Trav1 Gene Detail
Summary
  • Symbol
    Trav1
  • Name
    T cell receptor alpha variable 1
Location &
Maps
more
  • Sequence Map
    Chr14:52665424-52666333 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.94 cM
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651476
gene segment Chr14:52665385-52666333 (+)
129S1/SvImJ ENSMUSG00200044422
gene segment Chr14:41456293-41457269 (+)
A/J ENSMUSG00195026466
gene segment Chr14:41685514-41686490 (+)
AKR/J ENSMUSG00220040473
gene segment Chr14:41041412-41042384 (+)
BALB/cJ ENSMUSG00180053062
gene segment Chr14:41314484-41315456 (+)
C3H/HeJ ENSMUSG00175051702
gene segment Chr14:42968646-42969618 (+)
C57BL/6NJ ENSMUSG00215048820
gene segment Chr14:41676612-41677560 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002214
gene segment Chr14:44447997-44448931 (+)
CAST/EiJ ENSTCUG00005050609
gene segment Chr14:43537732-43538684 (+)
CBA/J ENSMUSG00210046558
gene segment Chr14:41668069-41669045 (+)
DBA/2J ENSMUSG00185055646
gene segment Chr14:46585396-46586344 (+)
FVB/NJ ENSMUSG00205048449
gene segment Chr14:40919839-40920815 (+)
JF1/MsJ ENSUMUG00000049366
gene segment Chr14:58495922-58496872 (+)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190047474
gene segment Chr14:41354034-41355006 (+)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010042101
gene segment Chr14:40881092-40882064 (+)
SPRET/EiJ ENSMSPG00010048369
gene segment Chr14:44586816-44587732 (+)
WSB/EiJ ENSIUOG00005041086
gene segment Chr14:41074222-41075178 (+)



Homology
more
  • Human Ortholog
    TRAV1-1, T cell receptor alpha variable 1-1
  • Vertebrate Orthologs
    19
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRAV1-1, T cell receptor alpha variable 1-1
  • Synonyms
    TCRAV1S1, TCRAV7S1, TRAV11
  • Links
    NCBI Gene ID: 28693
    UniProt: A0A0B4J248

  • Chr Location
    14q11.2; chr14:21621838-21622567 (+)  GRCh38

  • Human Ortholog
    TRAV1-2, T cell receptor alpha variable 1-2
  • Synonyms
    TCRAV1S2, TCRAV7S2, TRAV12
  • Links
    NCBI Gene ID: 28692
    UniProt: A0A0B4J238

  • Chr Location
    14q11.2; chr14:21642889-21643586 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    • UniProt
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 627171 NCBI Gene Model | MGI Sequence Detail 910 C57BL/6J ±  kb
    polypeptide A0A075B5Z4 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR013106 Immunoglobulin V-set domain
      IPR051006 T cell receptor variable domain
    Molecular
    Reagents
    less

    • Microarray probesets 1
    References
    more
    • Summaries
      All 16
      Phenotypes 7
    • Earliest
      J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory