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Prl2c1 Gene Detail
Summary
  • Symbol
    Prl2c1
  • Name
    Prolactin family 2, subfamily c, member 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649927
    NCBI Gene: 666317
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:28033325-28041771 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.63 cM
Strain
Comparison
more
  • SNPs within 2kb
    247 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649927
 protein coding gene Chr13:28033324-28041774 (+)
129S1/SvImJ ENSMUSG00200028706
 protein coding gene Chr13:25193153-25201656 (+)
A/J ENSMUSG00195036652
 protein coding gene Chr13:24338449-24346913 (+)
AKR/J ENSMUSG00220012470
 protein coding gene Chr13:24149868-24158314 (+)
BALB/cJ ENSMUSG00180022241
 protein coding gene Chr13:24643660-24652109 (+)
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215007835
 protein coding gene Chr13:24798272-24806746 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018379
 protein coding gene Chr13:23501425-23509985 (+)
CAST/EiJ ENSTCUG00005009386
 protein coding gene Chr13:24820709-24829171 (+)
CBA/J ENSMUSG00210026772
 protein coding gene Chr13:24610525-24618975 (+)
DBA/2J ENSMUSG00185020557
 protein coding gene Chr13:25425454-25433900 (+)
FVB/NJ ENSMUSG00205018501
 protein coding gene Chr13:24426825-24435273 (+)
JF1/MsJ ENSUMUG00000009660
 protein coding gene Chr13:25070341-25078844 (+)
LP/J ENSMUSG00230017645
 protein coding gene Chr13:34753893-34762339 (+)
NOD/ShiLtJ ENSMUSG00190025950
 protein coding gene Chr13:24407463-24415907 (+)
NZO/HlLtJ ENSMUSG00225044736
 protein coding gene Chr13:28533075-28541521 (+)
PWK/PhJ ENSLUMG00010028001
 protein coding gene Chr13:23886217-23894711 (+)
SPRET/EiJ ENSMSPG00010023440
 protein coding gene Chr13:23880735-23889164 (+)
WSB/EiJ ENSIUOG00005015956
 protein coding gene Chr13:23983193-23991687 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Prl2c1
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062551 Ensembl Gene Model | MGI Sequence Detail 8447 C57BL/6J ±  kb
transcript ENSMUST00000110335 Ensembl | MGI Sequence Detail 852 Not Applicable  
polypeptide ENSMUSP00000105964 Ensembl | MGI Sequence Detail 228 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR018116 Somatotropin hormone, conserved site
    IPR001400 Somatotropin/prolactin
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 22
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:179988 Hayakawa K, et al., Bridging sequence diversity and tissue-specific expression by DNA methylation in genes of the mouse prolactin superfamily. Mamm Genome. 2012 Jun;23(5-6):336-45
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory