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Lipo1 Gene Detail
Summary
  • Symbol
    Lipo1
  • Name
    lipase, member O1
  • Synonyms
    Gm5097
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647308
    NCBI Gene: 329055
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:33753437-33764852 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 29.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    443 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647308
 protein coding gene Chr19:33752898-33764859 (-)
129S1/SvImJ no annotation
A/J ENSMUSG00195011082
 protein coding gene Chr19:30640040-30652003 (-)
AKR/J ENSMUSG00220017237
 protein coding gene Chr19:30535525-30547488 (-)
BALB/cJ ENSMUSG00180029310
 protein coding gene Chr19:30968929-30980895 (-)
C3H/HeJ ENSMUSG00175039237
 protein coding gene Chr19:30364894-30376855 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005018234
 protein coding gene Chr19:30037435-30049441 (-)
CBA/J ENSMUSG00210027874
 protein coding gene Chr19:30417918-30429881 (-)
DBA/2J ENSMUSG00185030980
 protein coding gene Chr19:30973199-30985162 (-)
FVB/NJ ENSMUSG00205006296
 protein coding gene Chr19:30221881-30233870 (-)
JF1/MsJ ENSUMUG00000033472
 protein coding gene Chr19:31161748-31173751 (-)
LP/J ENSMUSG00230033765
 protein coding gene Chr19:31760062-31772023 (-)
NOD/ShiLtJ ENSMUSG00190021100
 protein coding gene Chr19:30343125-30355086 (-)
NZO/HlLtJ ENSMUSG00225029226
 protein coding gene Chr19:35361280-35373550 (-)
PWK/PhJ ENSLUMG00010001226
 protein coding gene Chr19:30529900-30541882 (-)
SPRET/EiJ ENSMSPG00010035054
 protein coding gene Chr19:30221515-30232671 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 329055 NCBI Gene Model | MGI Sequence Detail 11416 C57BL/6J ±  kb
transcript NM_001323065 RefSeq | MGI Sequence Detail 1697 C57BL/6  
polypeptide NP_001309994 RefSeq | MGI Sequence Detail 399 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR029058 Alpha/Beta hydrolase fold
    IPR025483 Lipase, eukaryotic
    IPR006693 Partial AB-hydrolase lipase domain
References
more
  • Summaries
    All 12
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:122599 Ozyildirim AM, et al., The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts. Invest Ophthalmol Vis Sci. 2005 May;46(5):1572-80
  • Latest
    J:164564 Holmes RS, et al., Comparative studies of mammalian acid lipases: Evidence for a new gene family in mouse and rat (Lipo). Comp Biochem Physiol Part D Genomics Proteomics. 2010 Sep;5(3):217-26
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory