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Tmem200b Gene Detail
Summary
  • Symbol
    Tmem200b
  • Name
    transmembrane protein 200B
  • Synonyms
    EG623230
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646343
    NCBI Gene: 623230
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:131648511-131650451 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 64.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646343
protein coding gene Chr4:131648511-131651267 (+)
129S1/SvImJ ENSMUSG00200019507
protein coding gene Chr4:125102655-125104595 (+)
A/J ENSMUSG00195041081
protein coding gene Chr4:126427696-126429636 (+)
AKR/J ENSMUSG00220039575
protein coding gene Chr4:125419452-125421392 (+)
BALB/cJ ENSMUSG00180042440
protein coding gene Chr4:124061314-124063254 (+)
C3H/HeJ ENSMUSG00175043413
protein coding gene Chr4:125073739-125075679 (+)
C57BL/6NJ ENSMUSG00215048904
protein coding gene Chr4:126577632-126579572 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026556
protein coding gene Chr4:121563668-121565037 (+)
CAST/EiJ ENSTCUG00005047464
protein coding gene Chr4:125967489-125969425 (+)
CBA/J ENSMUSG00210052955
protein coding gene Chr4:124702697-124704637 (+)
DBA/2J ENSMUSG00185048528
protein coding gene Chr4:126235150-126237090 (+)
FVB/NJ ENSMUSG00205027858
protein coding gene Chr4:124475881-124477821 (+)
JF1/MsJ ENSUMUG00000039113
protein coding gene Chr4:126899213-126901153 (+)
LP/J ENSMUSG00230033199
protein coding gene Chr4:130041183-130043123 (+)
NOD/ShiLtJ ENSMUSG00190040223
protein coding gene Chr4:124467457-124469397 (+)
NZO/HlLtJ ENSMUSG00225026073
protein coding gene Chr4:135945891-135947831 (+)
PWK/PhJ ENSLUMG00010046683
protein coding gene Chr4:123920548-123922488 (+)
SPRET/EiJ ENSMSPG00010035799
protein coding gene Chr4:125982722-125984658 (+)
WSB/EiJ ENSIUOG00005034100
protein coding gene Chr4:124354296-124356235 (+)



Homology
more
  • Human Ortholog
    TMEM200B, transmembrane protein 200B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM200B, transmembrane protein 200B
  • Synonyms
    TTMB
  • Links
    NCBI Gene ID: 399474
    UniProt: Q69YZ2

  • Chr Location
    1p35.3; chr1:29119429-29123918 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Tmem200b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070720 Ensembl Gene Model | MGI Sequence Detail 1941 C57BL/6J ±  kb
transcript ENSMUST00000238733 Ensembl | MGI Sequence Detail 961 Not Applicable  
polypeptide ENSMUSP00000158757 Ensembl | MGI Sequence Detail 284 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018787 Protein of unknown function DUF2371, TMEM200
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 16
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory