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Ighv3-8 Gene Detail
Summary
  • Symbol
    Ighv3-8
  • Name
    immunoglobulin heavy variable 3-8
Location &
Maps
more
  • Sequence Map
    Chr12:114285996-114286286 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    20
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645298
gene segment Chr12:114285947-114286421 (-)
129S1/SvImJ ENSMUSG00200028473
gene segment Chr12:106033309-106033783 (-)
A/J ENSMUSG00195049009
gene segment Chr12:108787541-108788015 (-)
AKR/J ENSMUSG00220042621
gene segment Chr12:106414157-106414631 (-)
BALB/cJ ENSMUSG00180052142
gene segment Chr12:108265415-108265889 (-)
C3H/HeJ ENSMUSG00175047492
gene segment Chr12:110403967-110404441 (-)
C57BL/6NJ ENSMUSG00215048876
gene segment Chr12:107075519-107075993 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0000045
gene segment Chr12:108875532-108876006 (-)
CAST/EiJ ENSTCUG00005042341
gene segment Chr12:107286711-107287182 (-)
CBA/J ENSMUSG00210036543
gene segment Chr12:107480466-107480940 (-)
DBA/2J ENSMUSG00185032491
gene segment Chr12:109448648-109449122 (-)
FVB/NJ ENSMUSG00205045535
gene segment Chr12:106540989-106541463 (-)
JF1/MsJ ENSUMUG00000027256
gene segment Chr12:114083177-114083651 (-)
LP/J ENSMUSG00230047013
gene segment Chr12:116338440-116338914 (-)
NOD/ShiLtJ ENSMUSG00190033318
gene segment Chr12:105921560-105922034 (-)
NZO/HlLtJ ENSMUSG00225044610
gene segment Chr12:118221644-118222118 (-)
PWK/PhJ ENSLUMG00010050066
gene segment Chr12:107759911-107760385 (-)
PWK/PhJ ENSLUMG00010052219
gene segment Chr12:107772566-107773040 (-)
SPRET/EiJ ENSMSPG00010024845
gene segment Chr12:110486530-110487004 (-)
WSB/EiJ ENSIUOG00005042976
gene segment Chr12:106924598-106925072 (-)



Homology
more
  • Human Ortholog
    IGHV4-39, immunoglobulin heavy variable 4-39
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV4-39, immunoglobulin heavy variable 4-39
  • Synonyms
    IGHV439, VH
  • Links
    NCBI Gene ID: 28394
    UniProt: P01824

  • Chr Location
    14q32.33; chr14:106421709-106422218 (-)  GRCh38

  • Human Ortholog
    IGHV6-1, immunoglobulin heavy variable 6-1
  • Synonyms
    IGHV61, VH
  • Links
    NCBI Gene ID: 28385
    UniProt: A0A0B4J1U7

  • Chr Location
    14q32.33; chr14:105939754-105940253 (-)  GRCh38

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 780831 NCBI Gene Model | MGI Sequence Detail 291 C57BL/6J ±  kb
polypeptide A0A075B5T0 UniProt | EBI | MGI Sequence Detail 131 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003599 Immunoglobulin domain subtype
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 9
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory