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Cstdc4 Gene Detail
Summary
  • Symbol
    Cstdc4
  • Name
    cystatin domain containing 4
  • Synonyms
    Gm5483
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645124
    NCBI Gene: 433016
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:36004582-36008481 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    249 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645124
 protein coding gene Chr16:36004582-36008481 (+)
129S1/SvImJ ENSMUSG00200027058
 protein coding gene Chr16:33023961-33027848 (+)
A/J ENSMUSG00195010969
 protein coding gene Chr16:32575591-32579488 (+)
AKR/J ENSMUSG00220026140
 protein coding gene Chr16:32863356-32867241 (+)
BALB/cJ ENSMUSG00180012140
 protein coding gene Chr16:32791250-32795151 (+)
C3H/HeJ ENSMUSG00175029485
 protein coding gene Chr16:32927862-32931749 (+)
C57BL/6NJ ENSMUSG00215019373
 protein coding gene Chr16:32775857-32779718 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005029871
 protein coding gene Chr16:33192424-33196416 (+)
CBA/J ENSMUSG00210026604
 protein coding gene Chr16:32984977-32988864 (+)
DBA/2J ENSMUSG00185022431
 protein coding gene Chr16:32887974-32891859 (+)
FVB/NJ ENSMUSG00205016205
 protein coding gene Chr16:32923352-32927241 (+)
JF1/MsJ ENSUMUG00000029060
 protein coding gene Chr16:33102214-33105952 (+)
LP/J ENSMUSG00230025870
 protein coding gene Chr16:35544031-35547918 (+)
NOD/ShiLtJ ENSMUSG00190021388
 protein coding gene Chr16:33084161-33088054 (+)
NZO/HlLtJ ENSMUSG00225039192
 protein coding gene Chr16:38643366-38647253 (+)
PWK/PhJ ENSLUMG00010027567
 protein coding gene Chr16:33006513-33010255 (+)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005025015
 protein coding gene Chr16:33044370-33048259 (+)



Homology
more
  • Human Ortholog
    CSTA, cystatin A
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSTA, cystatin A
  • Synonyms
    AREI, PSS4, STF1, STFA
  • Links
    NCBI Gene ID: 1475
    UniProt: P01040

  • Chr Location
    3q21.1; chr3:122325248-122341969 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CSTA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 433016 NCBI Gene Model | MGI Sequence Detail 3900 C57BL/6J ±  kb
transcript NM_001082547 RefSeq | MGI Sequence Detail 414 C57BL/6  
polypeptide NP_001076016 RefSeq | MGI Sequence Detail 97 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000010 Cystatin domain
    IPR046350 Cystatin superfamily
    IPR001713 Proteinase inhibitor I25A, stefin
    IPR018073 Proteinase inhibitor I25, cystatin, conserved site
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
Other
Accession IDs
less
MGI:6275074
References
more
  • Summaries
    All 12
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory