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Csta3 Gene Detail
Summary
  • Symbol
    Csta3
  • Name
    cystatin A family member 3
  • Synonyms
    Gm5416
Location &
Maps
more
  • Sequence Map
    Chr16:36030773-36038158 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    221 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644688
protein coding gene Chr16:36030773-36038158 (+)
129S1/SvImJ ENSMUSG00200027305
protein coding gene Chr16:33050137-33057575 (+)
A/J ENSMUSG00195010987
protein coding gene Chr16:32601775-32609214 (+)
AKR/J ENSMUSG00220026815
protein coding gene Chr16:32889543-32896934 (+)
BALB/cJ ENSMUSG00180012693
protein coding gene Chr16:32817448-32824887 (+)
C3H/HeJ ENSMUSG00175028800
protein coding gene Chr16:32954066-32961455 (+)
C57BL/6NJ ENSMUSG00215019415
protein coding gene Chr16:32801878-32809225 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005029885
protein coding gene Chr16:33218730-33226117 (+)
CBA/J ENSMUSG00210026633
protein coding gene Chr16:33011187-33018572 (+)
DBA/2J ENSMUSG00185022878
protein coding gene Chr16:32914180-32921565 (+)
FVB/NJ ENSMUSG00205015702
protein coding gene Chr16:32949539-32956983 (+)
JF1/MsJ ENSUMUG00000028581
protein coding gene Chr16:33128192-33135616 (+)
LP/J ENSMUSG00230031918
protein coding gene Chr16:35570199-35577634 (+)
NOD/ShiLtJ ENSMUSG00190021500
protein coding gene Chr16:33110332-33117771 (+)
NZO/HlLtJ ENSMUSG00225039274
protein coding gene Chr16:38669538-38676973 (+)
PWK/PhJ ENSLUMG00010028261
protein coding gene Chr16:33032502-33039616 (+)
SPRET/EiJ ENSMSPG00010016428
protein coding gene Chr16:32976304-32983682 (+)
WSB/EiJ ENSIUOG00005026543
protein coding gene Chr16:33070557-33077946 (+)



Homology
more
  • Human Ortholog
    CSTA, cystatin A
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSTA, cystatin A
  • Synonyms
    AREI, PSS4, STF1, STFA
  • Links
    NCBI Gene ID: 1475
    UniProt: P01040

  • Chr Location
    3q21.1; chr3:122325248-122341969 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human CSTA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 408196 NCBI Gene Model | MGI Sequence Detail 7386 C57BL/6J ±  kb
transcript NM_001082542 RefSeq | MGI Sequence Detail 294 C57BL/6  
polypeptide NP_001076011 RefSeq | MGI Sequence Detail 97 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:6274746
References
more
  • Summaries
    All 18
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/15/2026
MGI 6.29
The Jackson Laboratory