About   Help   FAQ
Neurl1b Gene Detail
Summary
  • Symbol
    Neurl1b
  • Name
    neuralized E3 ubiquitin protein ligase 1B
  • Synonyms
    C230078M08Rik, EG240055, Neur2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643092
    NCBI Gene: 240055
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26633833-26665295 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.18 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1020 from dbSNP Build 142
  • Strain Annotations
    21
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643092
 protein coding gene Chr17:26633803-26665323 (+)
129S1/SvImJ ENSMUSG00200047342
 protein coding gene Chr17:22078262-22109679 (+)
A/J ENSMUSG00195054356
 protein coding gene Chr17:23098515-23129961 (+)
AKR/J ENSMUSG00220053257
 protein coding gene Chr17:22142258-22173678 (+)
BALB/cJ ENSMUSG00180047827
 protein coding gene Chr17:22376346-22407765 (+)
C3H/HeJ ENSMUSG00175051927
 protein coding gene Chr17:22134525-22165937 (+)
C57BL/6NJ ENSMUSG00215049861
 protein coding gene Chr17:22143439-22173141 (+)
C57BL/6NJ ENSMUSG00215049875
 protein coding gene Chr17:22171970-22174844 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021280
 protein coding gene Chr17:22263907-22295153 (+)
CAST/EiJ ENSTCUG00005044229
 protein coding gene Chr17:22736936-22766649 (+)
CBA/J ENSMUSG00210050114
 protein coding gene Chr17:21973381-22004798 (+)
DBA/2J ENSMUSG00185053037
 protein coding gene Chr17:24186706-24218141 (+)
FVB/NJ ENSMUSG00205049180
 protein coding gene Chr17:22445444-22475165 (+)
FVB/NJ ENSMUSG00205049197
 protein coding gene Chr17:22474117-22476878 (+)
JF1/MsJ ENSUMUG00000056383
 protein coding gene Chr17:23639721-23669346 (+)
LP/J ENSMUSG00230055033
 protein coding gene Chr17:25582776-25614190 (+)
NOD/ShiLtJ ENSMUSG00190044458
 protein coding gene Chr17:22075432-22106874 (+)
NZO/HlLtJ ENSMUSG00225052320
 protein coding gene Chr17:27505785-27537223 (+)
PWK/PhJ ENSLUMG00010052174
 protein coding gene Chr17:21555243-21586819 (+)
SPRET/EiJ ENSMSPG00010043871
 protein coding gene Chr17:22881709-22910063 (+)
WSB/EiJ ENSIUOG00005040738
 protein coding gene Chr17:22832602-22862261 (+)



Homology
more
  • Human Ortholog
    NEURL1B, neuralized E3 ubiquitin protein ligase 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NEURL1B, neuralized E3 ubiquitin protein ligase 1B
  • Synonyms
    hNeur2, neur2, RNF67B
  • Links
    NCBI Gene ID: 54492
    UniProt: A8MQ27

  • Chr Location
    5q35.1; chr5:172641248-172691540 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    651
  • Tissues
    40
  • cDNA Data
    14
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 240055 NCBI Gene Model | MGI Sequence Detail 31463 C57BL/6J ±  kb
transcript NM_001081656 RefSeq | MGI Sequence Detail 6273 C57BL/6  
polypeptide Q0MW30 UniProt | EBI | MGI Sequence Detail 546 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    Genomic 2
    cDNA 14
    Primer pair 4
    Other 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442659
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory