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Igkv11-125 Gene Detail
Summary
  • Symbol
    Igkv11-125
  • Name
    immunoglobulin kappa variable 11-125
  • Synonyms
    ENSMUSG00000050218
Location &
Maps
more
  • Sequence Map
    Chr6:67890557-67891036 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 31.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642338
gene segment Chr6:67890557-67891036 (+)
129S1/SvImJ ENSMUSG00200012678
gene segment Chr6:64802830-64803309 (+)
A/J ENSMUSG00195043070
gene segment Chr6:64549247-64549726 (+)
AKR/J ENSMUSG00220044674
gene segment Chr6:64029959-64030438 (+)
BALB/cJ ENSMUSG00180042897
gene segment Chr6:64905130-64905609 (+)
C3H/HeJ ENSMUSG00175048616
gene segment Chr6:112544645-112545124 (-)
C57BL/6NJ ENSMUSG00215042987
gene segment Chr6:64879671-64880150 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0000068
gene segment Chr6:64819860-64820336 (+)
CAST/EiJ ENSTCUG00005035484
gene segment Chr6:65201158-65201637 (+)
CBA/J ENSMUSG00210039157
gene segment Chr6:64702644-64703123 (+)
DBA/2J ENSMUSG00185048770
gene segment Chr6:65265786-65266265 (+)
FVB/NJ ENSMUSG00205039400
gene segment Chr6:64685938-64686417 (+)
JF1/MsJ ENSUMUG00000039522
gene segment Chr6:64668023-64668502 (+)
LP/J ENSMUSG00230028360
gene segment Chr6:66388234-66388713 (+)
NOD/ShiLtJ ENSMUSG00190046186
gene segment Chr6:64609377-64609856 (+)
NZO/HlLtJ ENSMUSG00225019697
gene segment Chr6:68423025-68423504 (+)
PWK/PhJ ENSLUMG00010023256
gene segment Chr6:63810085-63810564 (+)
SPRET/EiJ ENSMSPG00010026449
gene segment Chr6:65982393-65982871 (+)
WSB/EiJ ENSIUOG00005023883
gene segment Chr6:65655988-65656464 (+)



Homology
more
  • Human Ortholog
    IGKV1-12, immunoglobulin kappa variable 1-12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV1-12, immunoglobulin kappa variable 1-12
  • Synonyms
    IGKV112, L19
  • Links
    NCBI Gene ID: 28940
    UniProt: A0A0C4DH73

  • Chr Location
    2p11.2; chr2:89040224-89040745 (-)  GRCh38

  • Human Ortholog
    IGKV1-33, immunoglobulin kappa variable 1-33
  • Synonyms
    IGKV133, O18
  • Links
    NCBI Gene ID: 28933

  • Chr Location
    2p11.2; chr2:89268001-89268506 (-)  GRCh38

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 243428 NCBI Gene Model | MGI Sequence Detail 480 C57BL/6J ±  kb
polypeptide P01650 UniProt | EBI | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR050150 Immunoglobulin Variable Light Chain
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 12
    Gene Ontology 2
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory