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Krt74 Pseudogene Detail
Summary
  • Symbol
    Krt74
  • Name
    keratin 74
  • Synonyms
    Kb37
Location &
Maps
more
  • Sequence Map
    Chr15:101662787-101671873 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    365 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629975
 pseudogene Chr15:101662694-101671939 (-)
129S1/SvImJ ENSMUSG00200052441
 pseudogene Chr15:98881440-98889695 (-)
A/J ENSMUSG00195046346
 pseudogene Chr15:98757885-98767129 (-)
AKR/J ENSMUSG00220049726
 pseudogene Chr15:98748035-98757299 (-)
BALB/cJ ENSMUSG00180046769
 pseudogene Chr15:98651450-98659708 (-)
C3H/HeJ ENSMUSG00175049257
 pseudogene Chr15:98937873-98947115 (-)
C57BL/6NJ ENSMUSG00215051912
 pseudogene Chr15:98703540-98712788 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020323
 protein coding gene Chr15:95593558-95601637 (-)
CAST/EiJ ENSTCUG00005046918
 pseudogene Chr15:98178446-98186635 (-)
CBA/J ENSMUSG00210032830
 pseudogene Chr15:98711047-98720289 (-)
DBA/2J ENSMUSG00185044973
 pseudogene Chr15:98748019-98757257 (-)
FVB/NJ ENSMUSG00205047238
 pseudogene Chr15:98452496-98461737 (-)
JF1/MsJ ENSUMUG00000057610
 pseudogene Chr15:98207457-98215658 (-)
LP/J ENSMUSG00230040268
 pseudogene Chr15:102105074-102113329 (-)
NOD/ShiLtJ ENSMUSG00190050883
 pseudogene Chr15:98687298-98696542 (-)
NZO/HlLtJ ENSMUSG00225028130
 pseudogene Chr15:102289395-102298602 (-)
PWK/PhJ ENSLUMG00010050634
 pseudogene Chr15:98420077-98428278 (-)
SPRET/EiJ ENSMSPG00010050133
 pseudogene Chr15:100212914-100221017 (-)
WSB/EiJ ENSIUOG00005041368
 pseudogene Chr15:98840264-98849520 (-)



Homology
more
  • Human Ortholog
    KRT74, keratin 74
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT74, keratin 74
  • Synonyms
    ADWH, ECTD7, HTSS2, HYPT3, K6IRS4, KRT5C, KRT6IRS4
  • Links
    NCBI Gene ID: 121391
    UniProt: Q7RTS7

  • Chr Location
    12q13.13; chr12:52565782-52573843 (-)  GRCh38
Human Diseases
more
  • Diseases
    3 with human KRT74 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    38 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    1
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      26
    • RefSeq
      1
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000067596 Ensembl Gene Model | MGI Sequence Detail 9087 C57BL/6J ±  kb
    transcript ENSMUST00000229279 Ensembl | MGI Sequence Detail 1489 Not Applicable  
    polypeptide Q6IFZ9 UniProt | EBI | MGI Sequence Detail 495 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 3
      Phenotypes 38
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory