About   Help   FAQ
Mir592 Gene Detail
Summary
  • Symbol
    Mir592
  • Name
    microRNA 592
  • Synonyms
    mir 592, mir-592, Mirn592, mmu-mir-592
Location &
Maps
more
  • Sequence Map
    Chr6:27936654-27936749 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 11.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629661
 miRNA gene Chr6:27936654-27936749 (-)
129S1/SvImJ ENSMUSG00200035642
 miRNA gene Chr6:24985172-24985267 (-)
A/J ENSMUSG00195009153
 miRNA gene Chr6:24951503-24951598 (-)
AKR/J ENSMUSG00220003924
 miRNA gene Chr6:24530760-24530855 (-)
BALB/cJ ENSMUSG00180022207
 miRNA gene Chr6:25083340-25083435 (-)
C3H/HeJ ENSMUSG00175020692
 miRNA gene Chr6:24942492-24942587 (-)
C57BL/6NJ ENSMUSG00215024829
 miRNA gene Chr6:24975169-24975264 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008007
 miRNA gene Chr6:22782257-22782352 (-)
CAST/EiJ ENSTCUG00005027277
 miRNA gene Chr6:24535981-24536076 (-)
CBA/J ENSMUSG00210005081
 miRNA gene Chr6:24963849-24963944 (-)
DBA/2J ENSMUSG00185021753
 miRNA gene Chr6:25067562-25067657 (-)
FVB/NJ ENSMUSG00205031667
 miRNA gene Chr6:25018798-25018893 (-)
JF1/MsJ ENSUMUG00000036294
 miRNA gene Chr6:24735646-24735741 (-)
LP/J ENSMUSG00230031747
 miRNA gene Chr6:26001936-26002031 (-)
NOD/ShiLtJ ENSMUSG00190033247
 miRNA gene Chr6:24831641-24831736 (-)
NZO/HlLtJ ENSMUSG00225014848
 miRNA gene Chr6:27966876-27966971 (-)
PWK/PhJ ENSLUMG00010024553
 miRNA gene Chr6:24533525-24533620 (-)
SPRET/EiJ ENSMSPG00010022815
 miRNA gene Chr6:24934375-24934470 (-)
WSB/EiJ ENSIUOG00005035582
 miRNA gene Chr6:25103033-25103128 (-)



Homology
more
  • Human Ortholog
    MIR592, microRNA 592
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR592, microRNA 592
  • Synonyms
    hsa-mir-592, mir-592, MIRN592
  • Links
    NCBI Gene ID: 693177

  • Chr Location
    chr7:127058088-127058184 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show partial perinatal lethality, with more males affected by lethality. Adults show reduced motor coordination, social interaction, and novel object curiosity, and increased grooming. Cortical neurogenesis is affected, with repressed intermediate progenitor cell to mature neuron transition.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    608
  • Tissues
    6
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 735266 NCBI Gene Model | MGI Sequence Detail 96 C57BL/6J ±  kb
    transcript NR_030420 RefSeq | MGI Sequence Detail 96 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 3
      Primer pair 2
      Other 1
    Other Database
    Links
    less
    miRBase MI0004127
    References
    more
    • Summaries
      All 15
      Developmental Gene Expression 4
      Gene Ontology 2
      Phenotypes 2
    • Earliest
      J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
    • Latest
      J:361665 Ding Z, et al., DEmiRNA-mRNA regulatory network reveals miR-122-5p as a regulatory factor of arginine metabolism in necrotizing enterocolitis. Front Genet. 2024;15:1480431
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory