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Mir543 Gene Detail
Summary
  • Symbol
    Mir543
  • Name
    microRNA 543
  • Synonyms
    mir 543, Mirn543, mmu-mir-543
Location &
Maps
more
  • Sequence Map
    Chr12:109683692-109683767 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 60.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619432
miRNA gene Chr12:109683692-109683767 (+)
129S1/SvImJ ENSMUSG00200026375
miRNA gene Chr12:101457457-101457532 (+)
A/J ENSMUSG00195044601
miRNA gene Chr12:103989370-103989445 (+)
AKR/J ENSMUSG00220044911
miRNA gene Chr12:101871652-101871727 (+)
BALB/cJ ENSMUSG00180048327
miRNA gene Chr12:103220615-103220690 (+)
C3H/HeJ ENSMUSG00175050870
miRNA gene Chr12:105799603-105799678 (+)
C57BL/6NJ ENSMUSG00215047558
miRNA gene Chr12:102493559-102493634 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007274
miRNA gene Chr12:104163159-104163234 (+)
CAST/EiJ ENSTCUG00005022008
miRNA gene Chr12:101971868-101971943 (+)
CBA/J ENSMUSG00210033084
miRNA gene Chr12:102861061-102861136 (+)
DBA/2J ENSMUSG00185028715
miRNA gene Chr12:104679596-104679671 (+)
FVB/NJ ENSMUSG00205041521
miRNA gene Chr12:101905470-101905545 (+)
JF1/MsJ ENSUMUG00000026098
miRNA gene Chr12:109437756-109437831 (+)
LP/J ENSMUSG00230031371
miRNA gene Chr12:111722339-111722414 (+)
NOD/ShiLtJ ENSMUSG00190040306
miRNA gene Chr12:83317588-83317663 (-)
NZO/HlLtJ ENSMUSG00225039262
miRNA gene Chr12:113481217-113481292 (+)
PWK/PhJ ENSLUMG00010044508
miRNA gene Chr12:102910265-102910340 (+)
SPRET/EiJ ENSMSPG00010024466
miRNA gene Chr12:105193272-105193347 (+)
WSB/EiJ ENSIUOG00005010430
miRNA gene Chr12:101902897-101902972 (+)



Homology
more
  • Human Ortholog
    MIR543, microRNA 543
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR543, microRNA 543
  • Synonyms
    hsa-mir-543, mir-543, MIRN543
  • Links
    NCBI Gene ID: 100126335

  • Chr Location
    chr14:101031987-101032064 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723881 NCBI Gene Model | MGI Sequence Detail 76 C57BL/6J ±  kb
transcript NR_030261 RefSeq | MGI Sequence Detail 76 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    Primer pair 1
    Other 3
Other Database
Links
less
miRBase MI0003519
References
more
  • Summaries
    All 21
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:106122 Sewer A, et al., Identification of clustered microRNAs using an ab initio prediction method. BMC Bioinformatics. 2005;6:267
  • Latest
    J:338912 Jones BT, et al., Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes Dev. 2023 Aug 8;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory