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CK137956 Gene Detail
Summary
  • Symbol
    CK137956
  • Name
    cDNA sequence CK137956
  • Feature Type
    protein coding gene
  • IDs
    MGI:3616080
    NCBI Gene: 635169
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:127821385-127864744 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 61.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1390 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3616080
 protein coding gene Chr4:127821385-127882072 (-)
129S1/SvImJ ENSMUSG00200013486
 protein coding gene Chr4:121260115-121303531 (-)
A/J ENSMUSG00195039627
 protein coding gene Chr4:122597983-122641342 (-)
AKR/J ENSMUSG00220020077
 protein coding gene Chr4:121585126-121628494 (-)
BALB/cJ ENSMUSG00180044891
 protein coding gene Chr4:120231692-120275053 (-)
C3H/HeJ ENSMUSG00175020851
 protein coding gene Chr4:121244367-121287726 (-)
C57BL/6NJ ENSMUSG00215049874
 protein coding gene Chr4:122741552-122784915 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026497
 protein coding gene Chr4:117713647-117756990 (-)
CAST/EiJ ENSTCUG00005045033
 protein coding gene Chr4:122133055-122176330 (-)
CBA/J ENSMUSG00210051396
 protein coding gene Chr4:120873229-120916580 (-)
DBA/2J ENSMUSG00185050114
 protein coding gene Chr4:122405820-122449180 (-)
FVB/NJ ENSMUSG00205015025
 protein coding gene Chr4:120627738-120671117 (-)
JF1/MsJ ENSUMUG00000009917
 protein coding gene Chr4:123053181-123096554 (-)
LP/J ENSMUSG00230028801
 protein coding gene Chr4:126197693-126241100 (-)
NOD/ShiLtJ ENSMUSG00190030662
 protein coding gene Chr4:120635379-120678813 (-)
NZO/HlLtJ ENSMUSG00225015247
 protein coding gene Chr4:132112763-132156121 (-)
PWK/PhJ ENSLUMG00010040647
 protein coding gene Chr4:120088905-120132300 (-)
SPRET/EiJ ENSMSPG00010034940
 protein coding gene Chr4:122163784-122207216 (-)
WSB/EiJ ENSIUOG00005039305
 protein coding gene Chr4:120484153-120527616 (-)



Homology
more
  • Human Ortholog
    C1orf94, chromosome 1 open reading frame 94
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C1orf94, chromosome 1 open reading frame 94
  • Links
    NCBI Gene ID: 84970
    UniProt: Q6P1W5

  • Chr Location
    1p35.1; chr1:34166883-34219131 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit male infertility. Testis weight is reduced and males exhibit azoospermia, arrest of spermiogenesis and an increase in apoptotic cells in the seminiferous tubules.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028813 Ensembl Gene Model | MGI Sequence Detail 43360 C57BL/6J ±  kb
    transcript ENSMUST00000030614 Ensembl | MGI Sequence Detail 2319 Not Applicable  
    polypeptide ENSMUSP00000030614 Ensembl | MGI Sequence Detail 596 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR031496 Protein of unknown function DUF4688
    • GlyGen
      B1AYM9 1 site
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 25
      Gene Ontology 1
      Phenotypes 12
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:345318 Chen Y, et al., Regulation of Miwi-mediated mRNA stabilization by Ck137956/Tssa is essential for male fertility. BMC Biol. 2023 Apr 17;21(1):89
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory