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Iho1 Gene Detail
Summary
  • Symbol
    Iho1
  • Name
    interactor of HORMAD1 1
  • Synonyms
    Ccdc36, Iho1
Location &
Maps
more
  • Sequence Map
    Chr9:108280810-108305683 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    780 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3612242
 protein coding gene Chr9:108280691-108309040 (-)
129S1/SvImJ ENSMUSG00200041374
 protein coding gene Chr9:105478696-105503568 (-)
A/J ENSMUSG00195038217
 protein coding gene Chr9:104697619-104722476 (-)
AKR/J ENSMUSG00220024526
 protein coding gene Chr9:105084946-105109804 (-)
BALB/cJ ENSMUSG00180019882
 protein coding gene Chr9:105014093-105038945 (-)
C3H/HeJ ENSMUSG00175038296
 protein coding gene Chr9:105356374-105381230 (-)
C57BL/6NJ ENSMUSG00215036271
 protein coding gene Chr9:105333581-105358455 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032687
 protein coding gene Chr9:103746536-103770813 (-)
CAST/EiJ ENSTCUG00005030440
 protein coding gene Chr9:105105960-105131005 (-)
CBA/J ENSMUSG00210038518
 protein coding gene Chr9:105203309-105228280 (-)
DBA/2J ENSMUSG00185038355
 protein coding gene Chr9:105365796-105390652 (-)
FVB/NJ ENSMUSG00205026068
 protein coding gene Chr9:105367161-105392024 (-)
JF1/MsJ ENSUMUG00000045532
 protein coding gene Chr9:105192656-105217633 (-)
LP/J ENSMUSG00230050165
 protein coding gene Chr9:105507523-105532393 (-)
NOD/ShiLtJ ENSMUSG00190040756
 protein coding gene Chr9:105004227-105029088 (-)
NZO/HlLtJ ENSMUSG00225023657
 protein coding gene Chr9:105739025-105763880 (-)
PWK/PhJ ENSLUMG00010038463
 protein coding gene Chr9:105154442-105179430 (-)
SPRET/EiJ ENSMSPG00010031442
 protein coding gene Chr9:106981243-107006190 (-)
WSB/EiJ ENSIUOG00005037894
 protein coding gene Chr9:104454735-104480303 (-)



Homology
more
  • Human Ortholog
    IHO1, interactor of HORMAD1 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IHO1, interactor of HORMAD1 1
  • Synonyms
    CCDC36, CT74, LELA1
  • Links
    NCBI Gene ID: 339834
    UniProt: Q8IYA8

  • Chr Location
    3p21.31; chr3:49191309-49258106 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    679
  • Tissues
    13
  • cDNA Data
    7
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047220 Ensembl Gene Model | MGI Sequence Detail 24874 C57BL/6J ±  kb
transcript ENSMUST00000076592 Ensembl | MGI Sequence Detail 2890 Not Applicable  
polypeptide ENSMUSP00000075898 Ensembl | MGI Sequence Detail 574 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
Other
Accession IDs
less
MGI:6400271
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
  • Latest
    J:361361 Dereli I, et al., Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes. Nat Commun. 2024 Apr 5;15(1):2941
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory