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Tmem120b Gene Detail
Summary
  • Symbol
    Tmem120b
  • Name
    transmembrane protein 120B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3603158
    NCBI Gene: 330189
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123214329-123256272 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1117 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3603158
 protein coding gene Chr5:123206478-123256272 (+)
129S1/SvImJ ENSMUSG00200024881
 protein coding gene Chr5:116945081-116988423 (+)
A/J ENSMUSG00195009191
 protein coding gene Chr5:116466501-116509845 (+)
AKR/J ENSMUSG00220044225
 protein coding gene Chr5:115976878-116020201 (+)
BALB/cJ ENSMUSG00180033721
 protein coding gene Chr5:116581468-116624809 (+)
C3H/HeJ ENSMUSG00175021648
 protein coding gene Chr5:118596742-118640054 (+)
C57BL/6NJ ENSMUSG00215021023
 protein coding gene Chr5:116622571-116665910 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027718
 protein coding gene Chr5:116086307-116135103 (+)
CAST/EiJ ENSTCUG00005038755
 protein coding gene Chr5:115885858-115928035 (+)
CBA/J ENSMUSG00210008930
 protein coding gene Chr5:117347515-117390826 (+)
DBA/2J ENSMUSG00185048056
 protein coding gene Chr5:120398768-120442077 (+)
FVB/NJ ENSMUSG00205020651
 protein coding gene Chr5:116252815-116296150 (+)
JF1/MsJ ENSUMUG00000026409
 protein coding gene Chr5:123256688-123300252 (+)
LP/J ENSMUSG00230042238
 protein coding gene Chr5:124467079-124510419 (+)
NOD/ShiLtJ ENSMUSG00190036691
 protein coding gene Chr5:116273177-116316488 (+)
NZO/HlLtJ ENSMUSG00225013718
 protein coding gene Chr5:132155519-132198852 (+)
PWK/PhJ ENSLUMG00010041769
 protein coding gene Chr5:115154374-115197772 (+)
SPRET/EiJ ENSMSPG00010041116
 protein coding gene Chr5:118470119-118511201 (+)
WSB/EiJ ENSIUOG00005017553
 protein coding gene Chr5:118961383-119004728 (+)



Homology
more
  • Human Ortholog
    TMEM120B, transmembrane protein 120B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM120B, transmembrane protein 120B
  • Links
    NCBI Gene ID: 144404
    UniProt: A0PK00

  • Chr Location
    12q24.31; chr12:121712752-121783001 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    5
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Tmem120b
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    22 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    32
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 330189 NCBI Gene Model | MGI Sequence Detail 41944 C57BL/6J ±  kb
transcript NR_185160 RefSeq | MGI Sequence Detail 2685 C57BL/6  
polypeptide Q3TA38 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory