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Rtl8b Gene Detail
Summary
  • Symbol
    Rtl8b
  • Name
    retrotransposon Gag like 8B
  • Synonyms
    Cxx1b, Mart8c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3576504
    NCBI Gene: 553127
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:52671144-52672375 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 29.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    22
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3576504
protein coding gene ChrX:52671132-52672404 (-)
129S1/SvImJ ENSMUSG00200037336
protein coding gene ChrX:36572915-36574146 (-)
129S1/SvImJ ENSMUSG00200037333
protein coding gene ChrX:36546225-36547419 (-)
A/J ENSMUSG00195016362
protein coding gene ChrX:39629333-39630527 (+)
A/J ENSMUSG00195016351
protein coding gene ChrX:39602586-39603817 (+)
AKR/J ENSMUSG00220035732
protein coding gene ChrX:36128057-36129288 (-)
BALB/cJ ENSMUSG00180033287
protein coding gene ChrX:37068584-37069815 (-)
BALB/cJ ENSMUSG00180033266
protein coding gene ChrX:37041870-37043064 (-)
C3H/HeJ ENSMUSG00175039149
protein coding gene ChrX:40108557-40109788 (-)
C57BL/6NJ ENSMUSG00215047498
protein coding gene ChrX:37072073-37073304 (-)
C57BL/6NJ ENSMUSG00215047470
protein coding gene ChrX:37045383-37046577 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033077
protein coding gene ChrX:46200786-46201950 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210038525
protein coding gene ChrX:37326655-37327886 (-)
CBA/J ENSMUSG00210038500
protein coding gene ChrX:37299962-37301156 (-)
DBA/2J ENSMUSG00185032219
protein coding gene ChrX:48004004-48005198 (-)
DBA/2J ENSMUSG00185032226
protein coding gene ChrX:48030693-48031924 (-)
FVB/NJ ENSMUSG00205028889
protein coding gene ChrX:35655470-35656701 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230027857
protein coding gene ChrX:54551256-54552450 (-)
NOD/ShiLtJ ENSMUSG00190034394
protein coding gene ChrX:36409541-36410735 (-)
NOD/ShiLtJ ENSMUSG00190034421
protein coding gene ChrX:36436224-36437455 (-)
NZO/HlLtJ ENSMUSG00225042671
protein coding gene ChrX:59728375-59729570 (-)
NZO/HlLtJ ENSMUSG00225042675
protein coding gene ChrX:59755064-59756295 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RTL8A, retrotransposon Gag like 8A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RTL8A, retrotransposon Gag like 8A
  • Synonyms
    CXX1b, FAM127B, MAR8A, SIRH6
  • Links
    NCBI Gene ID: 26071
    UniProt: Q9BWD3

  • Chr Location
    Xq26.3; chrX:135050932-135052196 (-)  GRCh38

  • Human Ortholog
    RTL8B, retrotransposon Gag like 8B
  • Synonyms
    CXX1c, FAM127C, MAR8B, SIRH4
  • Links
    NCBI Gene ID: 441518
    UniProt: Q17RB0

  • Chr Location
    Xq26.3; chrX:135020513-135022542 (-)  GRCh38

  • Human Ortholog
    RTL8C, retrotransposon Gag like 8C
  • Synonyms
    CXX1, FAM127A, Mar8, MAR8C, Mart8, MART8C, SIRH5
  • Links
    NCBI Gene ID: 8933
    UniProt: A6ZKI3

  • Chr Location
    Xq26.3; chrX:135032355-135033546 (+)  GRCh38

Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067924 Ensembl Gene Model | MGI Sequence Detail 1232 C57BL/6J ±  kb
transcript ENSMUST00000088778 Ensembl | MGI Sequence Detail 1232 Not Applicable  
polypeptide ENSMUSP00000086157 Ensembl | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:5906154
References
more
  • Summaries
    All 13
    Developmental Gene Expression 1
  • Earliest
    J:96508 Brandt J, et al., Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene. 2005 Jan 17;345(1):101-11
  • Latest
    J:336757 Mohan HM, et al., RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. Cell Mol Life Sci. 2022 Mar 5;79(3):176

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/15/2026
MGI 6.29
The Jackson Laboratory