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AK157302 Gene Detail
Summary
  • Symbol
    AK157302
  • Name
    cDNA sequence AK157302
Location &
Maps
more
  • Sequence Map
    Chr13:21679393-21681307 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 7.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3574096
 protein coding gene Chr13:21679393-21681316 (+)
129S1/SvImJ ENSMUSG00200012173
 protein coding gene Chr13:18878311-18880234 (+)
A/J ENSMUSG00195034180
 protein coding gene Chr13:18022310-18024233 (+)
AKR/J ENSMUSG00220027557
 protein coding gene Chr13:17937666-17939589 (+)
BALB/cJ ENSMUSG00180031967
 protein coding gene Chr13:18383597-18385520 (+)
C3H/HeJ ENSMUSG00175032935
 protein coding gene Chr13:18488732-18490655 (+)
C57BL/6NJ ENSMUSG00215019334
 protein coding gene Chr13:18435367-18437290 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J ENSMUSG00210028823
 protein coding gene Chr13:18350289-18352212 (+)
DBA/2J ENSMUSG00185013389
 protein coding gene Chr13:19044657-19046580 (+)
FVB/NJ ENSMUSG00205020985
 protein coding gene Chr13:18194114-18196037 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230033165
 protein coding gene Chr13:28438700-28440623 (+)
NOD/ShiLtJ ENSMUSG00190019535
 protein coding gene Chr13:18303470-18305393 (+)
NZO/HlLtJ ENSMUSG00225045284
 protein coding gene Chr13:22199534-22201457 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005031183
 protein coding gene Chr13:17679437-17681360 (+)



Homology
more
  • Human Ortholog
    ISCA1, iron-sulfur cluster assembly 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ISCA1, iron-sulfur cluster assembly 1
  • Synonyms
    HBLD2, hIscA, hIscA1, ISA1, MMDS5
  • Links
    NCBI Gene ID: 81689
    UniProt: Q9BUE6

  • Chr Location
    9q21.33; chr9:86264546-86283102 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ISCA1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
  • All Sequences
    21
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 432732 NCBI Gene Model | MGI Sequence Detail 1915 C57BL/6J ±  kb
polypeptide I3ITR1 UniProt | EBI | MGI Sequence Detail 129 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR000361 Core domain, A-type assembly protein ATAP
    IPR016092 FeS A-type assembly protein ATAP
    IPR017870 FeS cluster insertion, C-terminal, conserved site
    IPR035903 HesB-like domain superfamily
    IPR050322 Iron-sulfur cluster assembly and transfer HesB/IscA
References
more
  • Summaries
    All 19
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory