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Gene Expression Data
Assay Details
Assay
Reference: J:79514 Burke Z, et al., Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev. 2002 Oct;118(1-2):147
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3529593
Gene symbol: Prox1
Gene name: prospero homeobox 1
Reporter: lacZ
Antibody: anti-B-galactosidase (55976)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A 1A: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: brown - Prox1; blue - Foxa2 (assay MGI:3529577). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present Regionally restricted 4A 1A Expression is present in the endoderm of the dorsal hindgut.

Specimen 4A 2A: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: brown - Prox1; blue - Foxa2 (assay MGI:3529577). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present Regionally restricted 4A 2A Expression is present in the endoderm of the dorsal hindgut.
TS13: notochordal plate Present 4A 2A

Specimen 4A 3A: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: brown - Prox1; blue - Foxa2 (assay MGI:3529577). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present Regionally restricted 4A 3A Although expression is not present in more lateral and ventral regions, it is present elsewhere.
TS13: notochord Present 4A 3A

Specimen 4B 1B: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: brown - Prox1; blue - Shh (assay MGI:3529582). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: notochord Present 4B 1B Expression is present in the posterior notochord.
TS13: hindgut diverticulum Present Regionally restricted 4B 1B Expression is present in the dorsal hindgut.

Specimen 4B 2B: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: brown - Prox1; blue - Shh (assay MGI:3529582). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: notochord Present 4B 2B Expression is present in the posterior notochord.
TS13: hindgut diverticulum Present Regionally restricted 4B 2B Expression is present in the dorsal hindgut.

Specimen 4B 3B: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: brown - Prox1; blue - Shh (assay MGI:3529582). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: notochord Present 4B 3B Expression is present in the posterior notochord.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory