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Gene Expression Data
Assay Details
Assay
Reference: J:79514 Burke Z, et al., Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev. 2002 Oct;118(1-2):147
Assay type: RNA in situ
MGI Accession ID: MGI:3529582
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe51
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2F: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Absent 2F There is no expression in the hepatic region.
TS13: septum transversum hepatic component Absent 2F There is no expression in the hepatic region.
TS13: notochord Present Regionally restricted 2F Expression is present in the notochord in the area around the regressing node.
TS13: hindgut diverticulum Present 2F Expression is present in the hindgut.
Specimen 3F: embryonic day 8.5 (more )
Note: After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Absent 3F There is no expression is the hepatic or pancreatic regions.
TS13: septum transversum hepatic component Absent 3F There is no expression is the hepatic or pancreatic regions.
Specimen 4B 1B: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: blue - Shh; brown - Prox1 (assay MGI:3529593). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: notochord Present 4B 1B Expression is present in the posterior notochord.
TS13: hindgut diverticulum Present Regionally restricted 4B 1B Expression is present in the ventral hindgut.
Specimen 4B 2B: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: blue - Shh; brown - Prox1 (assay MGI:3529593). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: notochord Present 4B 2B Expression is present in the posterior notochord.
TS13: hindgut diverticulum Present Regionally restricted 4B 2B Expression is present in the ventral hindgut.
Specimen 4B 3B: embryonic day 8.5; Prox1tm1Gco/Prox1+ (more )
Note: This embryo contains 9-10 somites. Double labeled: blue - Shh; brown - Prox1 (assay MGI:3529593). After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS13: notochord Present 4B 3B Expression is present in the posterior notochord.
TS13: hindgut diverticulum Present Regionally restricted 4B 3B Expression is present in the ventral hindgut.
Specimen 5F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: hepatic primordium Absent 5F There is no expression in the hepatic or pancreatic regions.
TS15: pancreas primordium Absent 5F There is no expression in the hepatic or pancreatic regions.
TS15: foregut Present 5F
Specimen 6F: embryonic day 9.5 (more )
Note: After whole mount staining, this embryo was embedded in gelatin and sucrose for cryosectioning.
Structure Level Pattern Image Note
TS15: hepatic primordium Absent 6F There is no expression in the hepatic and pancreatic regions.
TS15: pancreas primordium Absent 6F There is no expression in the hepatic and pancreatic regions.
TS15: foregut Present Regionally restricted 6F Expression is present in the foregut endoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory