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Tmem221 Gene Detail
Summary
  • Symbol
    Tmem221
  • Name
    transmembrane protein 221
  • Feature Type
    protein coding gene
  • IDs
    MGI:3525074
    NCBI Gene: 434325
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:72006882-72011515 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3525074
 protein coding gene Chr8:72006882-72011659 (-)
129S1/SvImJ ENSMUSG00200028987
 protein coding gene Chr8:66604513-66609148 (-)
A/J ENSMUSG00195015564
 protein coding gene Chr8:67052178-67056811 (-)
AKR/J ENSMUSG00220020988
 protein coding gene Chr8:67089657-67094293 (-)
BALB/cJ ENSMUSG00180026363
 protein coding gene Chr8:66787521-66792156 (-)
C3H/HeJ ENSMUSG00175019144
 protein coding gene Chr8:66989761-66994396 (-)
C57BL/6NJ ENSMUSG00215021436
 protein coding gene Chr8:66564497-66569130 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031192
 protein coding gene Chr8:63664453-63669006 (-)
CAST/EiJ ENSTCUG00005034940
 protein coding gene Chr8:66593537-66598168 (-)
CBA/J ENSMUSG00210034056
 protein coding gene Chr8:66833355-66837990 (-)
DBA/2J ENSMUSG00185011896
 protein coding gene Chr8:72992992-72997627 (-)
FVB/NJ ENSMUSG00205036329
 protein coding gene Chr8:66085325-66089961 (-)
JF1/MsJ ENSUMUG00000014147
 protein coding gene Chr8:75260536-75265169 (-)
LP/J ENSMUSG00230032512
 protein coding gene Chr8:76604655-76609290 (-)
NOD/ShiLtJ ENSMUSG00190027305
 protein coding gene Chr8:66747665-66752298 (-)
NZO/HlLtJ ENSMUSG00225046035
 protein coding gene Chr8:80004595-80009230 (-)
PWK/PhJ ENSLUMG00010029158
 protein coding gene Chr8:66726672-66731305 (-)
SPRET/EiJ ENSMSPG00010039908
 protein coding gene Chr8:68410509-68415115 (-)
WSB/EiJ ENSIUOG00005021030
 protein coding gene Chr8:67600641-67605278 (-)



Homology
more
  • Human Ortholog
    TMEM221, transmembrane protein 221
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM221, transmembrane protein 221
  • Synonyms
    Jiraiya
  • Links
    NCBI Gene ID: 100130519
    UniProt: A6NGB7

  • Chr Location
    19p13.11; chr19:17435509-17448668 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Tmem221
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043664 Ensembl Gene Model | MGI Sequence Detail 4634 C57BL/6J ±  kb
transcript ENSMUST00000052072 Ensembl | MGI Sequence Detail 1604 Not Applicable  
polypeptide ENSMUSP00000058317 Ensembl | MGI Sequence Detail 230 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory